Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11138121 | 0.81 | GAA (0.36) | ALDH1A1 | |
| SCHEMBL28694223 | 0.79 | — | — | |
| SCHEMBL11520478 | 0.75 | ALDH1A1 (0.38) | ALDH1A1MAPK1TDP1 | |
| SCHEMBL28701808 | 0.75 | — | — | |
| SCHEMBL5204544 | 0.74 | — | — | |
| SCHEMBL10701607 | 0.74 | — | — | |
| SCHEMBL1149749 | 0.72 | — | — | |
| Propionaldehyde SCHEMBL27381346 | 0.70 | TDP1 (0.50) | ALDH1A1MAPK1TDP1 | |
| SCHEMBL25285985 | 0.70 | PKM (0.30) | — | |
| SCHEMBL7960223 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090209557-A1 | DIHYDROOROTATE DEHYDROGENASE INHIBITORS WITH SELECTIVE ANTI-MALARIAL ACTIVITY | BOARD OF REGENTS, UNIVERSITY OF TEXAS SYSTEM UNIVERSITY OF WASHINGTON | 2009-08-20 | — | — | US | disclosed |
| EP-0435084-B2 | Process for the production of aldehydes | HOECHST AG (DE) | 1997-09-24 | — | — | EP | disclosed |
| US-5118867-A | Hydroformylation of an definically unsaturated compound, rhodium catalyst, a soluble ammonium salt of a sulfonated phosphorous acid triester | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-06-02 | — | — | US | disclosed |
| EP-0435084-A1 | Process for the production of aldehydes | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-07-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090209557-A1 | DIHYDROOROTATE DEHYDROGENASE INHIBITORS WITH SELECTIVE ANTI-MALARIAL ACTIVITY | DHODH, DHFR, G6PD | ALDH1A1 216/4885MAPK1 3480/4885TDP1 1059/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.