Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | CTSA | P10619 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | PNMT | P11086 | 1/20 | 0.43 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.43 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8771196 | 0.85 | ADRB2 (0.50) | KMT2AMEN1CTSACYP2D6NFKB1 | |
| SCHEMBL28829699 | 0.84 | AKR1B1 (0.43) | KMT2AMEN1CTSAAKR1B1 | |
| SCHEMBL5152957 | 0.82 | KMT2A (0.53) | KMT2AMEN1CTSATSHRAKR1B1 | |
| SCHEMBL31701959 | 0.81 | KMT2A (0.51) | KMT2AMEN1CTSATSHRAKR1B1 | |
| SCHEMBL5720933 | 0.81 | KMT2A (0.51) | KMT2AMEN1CTSATSHRAKR1B1 | |
| SCHEMBL381519 | 0.81 | KMT2A (0.51) | KMT2AMEN1CTSATSHRAKR1B1 | |
| SCHEMBL8770882 | 0.80 | MEN1 (0.44) | KMT2AMEN1KCNH2CYP1A2CYP3A4 | |
| SCHEMBL15206556 | 0.78 | MEN1 (0.46) | KMT2AMEN1KCNH2TSHRCYP1A2 | |
| SCHEMBL8771031 | 0.78 | CASP1 (0.48) | KMT2AMEN1TSHRCYP1A2CYP3A4 | |
| SCHEMBL7147316 | 0.77 | KCNH2 (0.54) | KMT2AMEN1KCNH2TSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0451668-B1 | Process for the production of optically active alkyl 3-aryl-3-hydroxypropionates | CHISSO CORP (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5202457-A | Enzyme catalyzed transesterification, resolution of optical active alkyl 3-aryl-3-hydroxypropionate | CHISSO CORPORATION (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0451668-A2 | Optically active alkyl 3-aryl-3-hydroxypropionates and a method for producing thereof | CHISSO CORPORATION (JP) | 1991-10-16 | — | — | EP | disclosed |