Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | PNMT | P11086 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8771003 | 0.88 | CASP1 (0.57) | CASP1NLRP3MEN1KMT2ARAB9A | |
| SCHEMBL16797627 | 0.87 | CASP1 (0.47) | CASP1NLRP3MEN1KMT2ARAB9A | |
| SCHEMBL8770882 | 0.85 | MEN1 (0.44) | MEN1KMT2ARAB9AALDH1A1LMNA | |
| SCHEMBL8770920 | 0.81 | MEN1 (0.42) | MEN1KMT2AALDH1A1LMNACYP1A2 | |
| SCHEMBL16797514 | 0.79 | KDM4E (0.46) | CASP1MEN1KMT2ARAB9ALMNA | |
| SCHEMBL10249906 | 0.78 | TSHR (0.47) | CASP1NLRP3MEN1KMT2AALDH1A1 | |
| SCHEMBL8770889 | 0.78 | KMT2A (0.53) | MEN1KMT2AALDH1A1LMNACYP1A2 | |
| SCHEMBL15129596 | 0.77 | MAPT (0.43) | CASP1NLRP3RAB9AALDH1A1HTT | |
| SCHEMBL16797693 | 0.77 | CA12 (0.46) | CASP1NLRP3MEN1KMT2AALDH1A1 | |
| SCHEMBL8770989 | 0.77 | NLRP3 (0.46) | NLRP3MEN1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0451668-B1 | Process for the production of optically active alkyl 3-aryl-3-hydroxypropionates | CHISSO CORP (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5202457-A | Enzyme catalyzed transesterification, resolution of optical active alkyl 3-aryl-3-hydroxypropionate | CHISSO CORPORATION (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0451668-A2 | Optically active alkyl 3-aryl-3-hydroxypropionates and a method for producing thereof | CHISSO CORPORATION (JP) | 1991-10-16 | — | — | EP | disclosed |