Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | PNMT | P11086 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3537300 | 0.87 | ADRB2 (0.53) | CYP2D6NFKB1ADRB2ADRB1HIF1A | |
| SCHEMBL28038462 | 0.87 | ADRB2 (0.53) | CYP2D6NFKB1ADRB2ADRB1HIF1A | |
| SCHEMBL8771031 | 0.85 | CASP1 (0.48) | MEN1KMT2ACYP2D6NFKB1CYP1A2 | |
| SCHEMBL8770920 | 0.84 | MEN1 (0.42) | MEN1KMT2ACYP2D6NFKB1CYP1A2 | |
| SCHEMBL13802834 | 0.83 | CYP1A2 (0.49) | MEN1KMT2ACYP2D6NFKB1CYP1A2 | |
| SCHEMBL2555679 | 0.81 | MEN1 (0.45) | MEN1KMT2ACYP2D6NFKB1CYP1A2 | |
| SCHEMBL8770889 | 0.80 | KMT2A (0.53) | MEN1KMT2ACYP2D6NFKB1CYP1A2 | |
| SCHEMBL23481478 | 0.77 | ADRB2 (0.49) | CYP2D6NFKB1ADRB2ADRB1HIF1A | |
| SCHEMBL22076575 | 0.77 | PPARG (0.37) | ALDH1A1MAPTRAB9A | |
| SCHEMBL7680090 | 0.76 | MEN1 (0.39) | MEN1KMT2ACYP2D6NFKB1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0451668-B1 | Process for the production of optically active alkyl 3-aryl-3-hydroxypropionates | CHISSO CORP (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5202457-A | Enzyme catalyzed transesterification, resolution of optical active alkyl 3-aryl-3-hydroxypropionate | CHISSO CORPORATION (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0451668-A2 | Optically active alkyl 3-aryl-3-hydroxypropionates and a method for producing thereof | CHISSO CORPORATION (JP) | 1991-10-16 | — | — | EP | disclosed |