Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8770895 | 0.83 | ADRB3 (0.53) | L3MBTL1MEN1KMT2AGLAADRB2 | |
| SCHEMBL13482971 | 0.83 | ADRB3 (0.53) | L3MBTL1MEN1KMT2AGLAADRB2 | |
| SCHEMBL30088535 | 0.83 | ADRB3 (0.53) | L3MBTL1MEN1KMT2AGLAADRB2 | |
| SCHEMBL8771001 | 0.83 | ALDH1A1 (0.38) | L3MBTL1MEN1ALDH1A1GAAKMT2A | |
| SCHEMBL29697542 | 0.82 | L3MBTL1 (0.47) | L3MBTL1LMNAMAPTRAB9AGAA | |
| SCHEMBL8770926 | 0.82 | L3MBTL1 (0.47) | L3MBTL1LMNAMAPTRAB9AGAA | |
| SCHEMBL17282243 | 0.82 | L3MBTL1 (0.46) | L3MBTL1LMNATNFMAPTRAB9A | |
| SCHEMBL8770893 | 0.81 | APP (0.39) | — | |
| SCHEMBL20154370 | 0.81 | L3MBTL1 (0.45) | L3MBTL1LMNATNFMAPTRAB9A | |
| SCHEMBL6341030 | 0.81 | L3MBTL1 (0.45) | L3MBTL1LMNATNFMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0451668-B1 | Process for the production of optically active alkyl 3-aryl-3-hydroxypropionates | CHISSO CORP (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5202457-A | Enzyme catalyzed transesterification, resolution of optical active alkyl 3-aryl-3-hydroxypropionate | CHISSO CORPORATION (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0451668-A2 | Optically active alkyl 3-aryl-3-hydroxypropionates and a method for producing thereof | CHISSO CORPORATION (JP) | 1991-10-16 | — | — | EP | disclosed |