Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL282281 | 0.84 | ADRB3 (0.46) | L3MBTL1 | |
| SCHEMBL30935351 | 0.83 | ALDH1A1 (0.44) | ALDH1A1MEN1HPGDKMT2AKDM4E | |
| SCHEMBL1504155 | 0.83 | ALDH1A1 (0.44) | ALDH1A1MEN1HPGDKMT2AKDM4E | |
| SCHEMBL1508450 | 0.83 | FFAR1 (0.45) | ALDH1A1KDM4EHTT | |
| SCHEMBL8770904 | 0.83 | L3MBTL1 (0.46) | ALDH1A1MEN1KMT2AL3MBTL1GAA | |
| SCHEMBL5872719 | 0.82 | ALDH1A1 (0.40) | ALDH1A1CNR2MEN1HPGDKMT2A | |
| SCHEMBL19090794 | 0.82 | ALDH1A1 (0.40) | ALDH1A1CNR2MEN1HPGDKMT2A | |
| Hydrochloric Acid SCHEMBL6371861 | 0.81 | ALDH1A1 (0.40) | ALDH1A1CNR2MEN1HPGDKMT2A | |
| Hydrochloric Acid SCHEMBL6778152 | 0.81 | ALDH1A1 (0.40) | ALDH1A1CNR2MEN1HPGDKMT2A | |
| SCHEMBL8771122 | 0.81 | SLC6A3 (0.49) | ALDH1A1KDM4EHTTTSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0451668-B1 | Process for the production of optically active alkyl 3-aryl-3-hydroxypropionates | CHISSO CORP (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5202457-A | Enzyme catalyzed transesterification, resolution of optical active alkyl 3-aryl-3-hydroxypropionate | CHISSO CORPORATION (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0451668-A2 | Optically active alkyl 3-aryl-3-hydroxypropionates and a method for producing thereof | CHISSO CORPORATION (JP) | 1991-10-16 | — | — | EP | disclosed |