Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.51 |
| ▸ | PRKCA | P17252 | 2/20 | 0.51 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.48 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8770948 | 0.86 | KMT2A (0.56) | ALOX5MAOBNR4A1NR4A2NR4A3 | |
| SCHEMBL6976976 | 0.86 | FFAR1 (0.50) | FFAR1PRKCAPRKCDALOX5MAOB | |
| SCHEMBL6976981 | 0.86 | FFAR1 (0.50) | FFAR1PRKCAPRKCDALOX5MAOB | |
| SCHEMBL8770978 | 0.85 | MAOB (0.57) | FFAR1ALOX5MAOBLTA4HNR4A1 | |
| SCHEMBL1508259 | 0.85 | MAOB (0.57) | FFAR1ALOX5MAOBLTA4HNR4A1 | |
| SCHEMBL5654433 | 0.83 | RIPK1 (0.51) | KDM4EMAPT | |
| SCHEMBL28857505 | 0.83 | RIPK1 (0.51) | KDM4EMAPT | |
| SCHEMBL232540 | 0.83 | LMNA (0.59) | FFAR1PRKCAPRKCDALOX5MAOB | |
| SCHEMBL8771189 | 0.82 | FFAR1 (0.63) | FFAR1ALOX5MAOBLTA4HNR4A1 | |
| SCHEMBL10317574 | 0.82 | FFAR1 (0.63) | FFAR1ALOX5MAOBLTA4HNR4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0451668-B1 | Process for the production of optically active alkyl 3-aryl-3-hydroxypropionates | CHISSO CORP (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5202457-A | Enzyme catalyzed transesterification, resolution of optical active alkyl 3-aryl-3-hydroxypropionate | CHISSO CORPORATION (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0451668-A2 | Optically active alkyl 3-aryl-3-hydroxypropionates and a method for producing thereof | CHISSO CORPORATION (JP) | 1991-10-16 | — | — | EP | disclosed |