Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8770972 | 0.84 | L3MBTL1 (0.43) | ALDH1A1MAPTNPSR1 | |
| SCHEMBL30605867 | 0.84 | L3MBTL1 (0.43) | ALDH1A1MAPTNPSR1 | |
| SCHEMBL4764216 | 0.83 | MAPT (0.47) | ALDH1A1KDM4EHTTCYP1A2CYP2C19 | |
| SCHEMBL8771019 | 0.83 | KCNA5 (0.38) | ALDH1A1HTTCYP1A2MAPTKMT2A | |
| SCHEMBL19090989 | 0.82 | ALDH1A1 (0.40) | GPR35ALDH1A1KDM4EHTTTRPA1 | |
| SCHEMBL19958914 | 0.82 | ALDH1A1 (0.40) | GPR35ALDH1A1KDM4EHTTTRPA1 | |
| Hydrochloric Acid SCHEMBL6224049 | 0.81 | ALDH1A1 (0.40) | GPR35ALDH1A1KDM4EHTTTRPA1 | |
| SCHEMBL8771001 | 0.80 | ALDH1A1 (0.38) | ALDH1A1KDM4EHTTKMT2AMEN1 | |
| SCHEMBL8770949 | 0.80 | CES2 (0.40) | ALDH1A1KDM4EHTTTRPA1CYP1A2 | |
| SCHEMBL8770916 | 0.80 | ALDH1A1 (0.42) | ALDH1A1KDM4EHTTTRPA1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0451668-B1 | Process for the production of optically active alkyl 3-aryl-3-hydroxypropionates | CHISSO CORP (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5202457-A | Enzyme catalyzed transesterification, resolution of optical active alkyl 3-aryl-3-hydroxypropionate | CHISSO CORPORATION (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0451668-A2 | Optically active alkyl 3-aryl-3-hydroxypropionates and a method for producing thereof | CHISSO CORPORATION (JP) | 1991-10-16 | — | — | EP | disclosed |