Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8770921 | 0.83 | KCNA5 (0.50) | KCNA5L3MBTL1 | |
| SCHEMBL8771047 | 0.83 | GPR35 (0.39) | MEN1KMT2APOLBCYP1A2HPGD | |
| SCHEMBL8770907 | 0.82 | MEN1 (0.48) | MEN1KMT2APOLBL3MBTL1CYP1A2 | |
| SCHEMBL28823648 | 0.82 | MEN1 (0.48) | MEN1KMT2APOLBL3MBTL1CYP1A2 | |
| SCHEMBL8770901 | 0.81 | CYP2D6 (0.38) | POLBHPGDALDH1A1 | |
| SCHEMBL24036698 | 0.81 | KCNA5 (0.37) | KCNA5MEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL25623852 | 0.81 | KCNA5 (0.37) | KCNA5MEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL4453208 | 0.79 | MAPT (0.44) | L3MBTL1MAPTRAB9AALDH1A1HTT | |
| SCHEMBL4453212 | 0.79 | MAPT (0.44) | L3MBTL1MAPTRAB9AALDH1A1HTT | |
| SCHEMBL8770904 | 0.79 | L3MBTL1 (0.46) | MEN1KMT2AL3MBTL1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0451668-B1 | Process for the production of optically active alkyl 3-aryl-3-hydroxypropionates | CHISSO CORP (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5202457-A | Enzyme catalyzed transesterification, resolution of optical active alkyl 3-aryl-3-hydroxypropionate | CHISSO CORPORATION (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0451668-A2 | Optically active alkyl 3-aryl-3-hydroxypropionates and a method for producing thereof | CHISSO CORPORATION (JP) | 1991-10-16 | — | — | EP | disclosed |