Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8770968 | 0.85 | SMN1; SMN2 (0.50) | L3MBTL1TACR1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL8770956 | 0.84 | L3MBTL1 (0.51) | L3MBTL1TACR1KMT2APOLBTNF | |
| SCHEMBL8770883 | 0.83 | L3MBTL1 (0.73) | L3MBTL1KMT2APOLBAOC3ALDH1A1 | |
| SCHEMBL8770966 | 0.83 | L3MBTL1 (0.46) | L3MBTL1KDM4EGAATACR1TNF | |
| SCHEMBL7352928 | 0.83 | KDM4E (0.45) | L3MBTL1KDM4EGAAKMT2APOLB | |
| SCHEMBL5468798 | 0.82 | AOC3 (0.57) | L3MBTL1KDM4EGAAKMT2AAOC3 | |
| SCHEMBL4453212 | 0.79 | MAPT (0.44) | L3MBTL1ALDH1A1 | |
| SCHEMBL8770904 | 0.79 | L3MBTL1 (0.46) | L3MBTL1GAAKMT2ATNFSMN1; SMN2 | |
| SCHEMBL4453208 | 0.79 | MAPT (0.44) | L3MBTL1ALDH1A1 | |
| SCHEMBL8771019 | 0.79 | KCNA5 (0.38) | L3MBTL1KMT2APOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117285413-A | Synthesis method of terbutaline key intermediate 3, 5-dihydroxyacetophenone | 重庆恩联生物科技有限公司 | 2023-12-26 | — | — | CN | claimed |
| CN-117285413-A | Synthesis method of terbutaline key intermediate 3, 5-dihydroxyacetophenone | 重庆恩联生物科技有限公司 | 2023-12-26 | — | — | CN | disclosed |
| CN-117285413-A | Synthesis method of terbutaline key intermediate 3, 5-dihydroxyacetophenone | 重庆恩联生物科技有限公司 | 2023-12-26 | — | — | CN | disclosed |
| EP-0451668-B1 | Process for the production of optically active alkyl 3-aryl-3-hydroxypropionates | CHISSO CORP (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5202457-A | Enzyme catalyzed transesterification, resolution of optical active alkyl 3-aryl-3-hydroxypropionate | CHISSO CORPORATION (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0451668-A2 | Optically active alkyl 3-aryl-3-hydroxypropionates and a method for producing thereof | CHISSO CORPORATION (JP) | 1991-10-16 | — | — | EP | disclosed |