Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | FGFR2 | P21802 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8770878 | 0.85 | L3MBTL1 (0.68) | L3MBTL1ALDH1A1ALOX15TSHRMAPK1 | |
| SCHEMBL8771183 | 0.85 | L3MBTL1 (0.50) | SMN1; SMN2L3MBTL1ALDH1A1POLBKMT2A | |
| SCHEMBL24643324 | 0.84 | ALOX15 (0.57) | L3MBTL1ALDH1A1ALOX15HPGDKMT2A | |
| SCHEMBL4811149 | 0.84 | ALOX15 (0.57) | L3MBTL1ALDH1A1ALOX15HPGDKMT2A | |
| SCHEMBL8770956 | 0.80 | L3MBTL1 (0.51) | L3MBTL1ALDH1A1POLBKMT2ATACR1 | |
| SCHEMBL8770966 | 0.79 | L3MBTL1 (0.46) | SMN1; SMN2L3MBTL1TACR1 | |
| SCHEMBL8771047 | 0.79 | GPR35 (0.39) | ALDH1A1CYP3A4HPGDTSHRMAPK1 | |
| SCHEMBL8771001 | 0.79 | ALDH1A1 (0.38) | SMN1; SMN2L3MBTL1ALDH1A1HPGDTSHR | |
| SCHEMBL8770949 | 0.79 | CES2 (0.40) | ALDH1A1TSHRKMT2A | |
| SCHEMBL5849064 | 0.78 | SMN1; SMN2 (0.45) | SMN1; SMN2L3MBTL1ALDH1A1ALOX15FGFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0451668-B1 | Process for the production of optically active alkyl 3-aryl-3-hydroxypropionates | CHISSO CORP (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5202457-A | Enzyme catalyzed transesterification, resolution of optical active alkyl 3-aryl-3-hydroxypropionate | CHISSO CORPORATION (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0451668-A2 | Optically active alkyl 3-aryl-3-hydroxypropionates and a method for producing thereof | CHISSO CORPORATION (JP) | 1991-10-16 | — | — | EP | disclosed |