SCHEMBL8771748

SCHEMBL8771748

CCC(NC(=O)Oc1ccccc1)C(=O)N(c1ccc(C#N)cc1)[C@@H](C)C(N)=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.40
MGLL Q99685 2/20 0.39
FAAH O00519 1/20 0.39
CYP11B1 P15538 1/20 0.35
CYP11B2 P19099 1/20 0.35
SLC1A3 P43003 1/20 0.35
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
ALDH1A1 P00352 2/20 0.34
KDM4E B2RXH2 1/20 0.34
MAPT P10636 1/20 0.34
THRB P10828 1/20 0.34
GFER P55789 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
CYP3A4 P08684 1/20 0.34
GAA P10253 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
CTSL P07711 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8607278 0.74 CTSL (0.40) MGLLMEN1KMT2ACTSLCTSB
SCHEMBL8603178 0.70 DPP4 (0.38) MEN1KMT2A
SCHEMBL8604298 0.69 CYP1A2 (0.57) CYP1A2FAAHSLC1A3MEN1KMT2A
SCHEMBL8771789 0.68 MTNR1A (0.47) MGLLFAAH
SCHEMBL8771945 0.67 MTNR1A (0.48) CTSLCTSBCTSSCTSKUTS2R
SCHEMBL27601849 0.67 MGLL (0.56) MGLLMEN1KMT2AALDH1A1KDM4E
SCHEMBL5113566 0.66 CYP1A2 (0.73) CYP1A2FAAHSLC1A3MEN1KMT2A
SCHEMBL8607249 0.66 TSHR (0.37) CYP3A4CYP2C19TSHR
SCHEMBL27440815 0.66 CYP1A2 (0.48) CYP1A2FAAHSLC1A3MEN1KMT2A
SCHEMBL27410642 0.65 SLC1A3 (0.50) CYP1A2FAAHSLC1A3MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648740-B1 AMINO ACID AMIDE DERIVATIVE, AGROHORTICULTURAL BACTERICIDE, AND PRODUCTION PROCESS KUMIAI CHEMICAL INDUSTRY CO (JP) 1997-10-08 EP disclosed
EP-0648740-A1 AMINO ACID AMIDE DERIVATIVE, AGROHORTICULTURAL BACTERICIDE, AND PRODUCTION PROCESS KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1995-04-19 EP disclosed