Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA9 | Q16790 | 3/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 7/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | STS | P08842 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1665682 | 0.83 | HPGDS (0.51) | FAAHCA2CA9CA12CA1 | |
| SCHEMBL1663618 | 0.80 | NPC1 (0.56) | — | |
| SCHEMBL1664301 | 0.71 | NPC1 (0.49) | — | |
| SCHEMBL3674376 | 0.70 | TRPV1 (0.76) | HIF1AEPAS1TRPV1 | |
| SCHEMBL1663685 | 0.70 | MAPT (0.53) | NAMPTHIF1A | |
| SCHEMBL14574170 | 0.69 | CA2 (0.71) | FAAHCA2CA9CA12CA1 | |
| Iodide SCHEMBL4160975 | 0.69 | FAAH (0.49) | FAAHCA2CA9CA12CA1 | |
| SCHEMBL25041147 | 0.69 | FAAH (0.90) | FAAHCA2CA9CA12CA1 | |
| SCHEMBL29198126 | 0.68 | RAB9A (0.70) | — | |
| Iodide SCHEMBL4157379 | 0.68 | FAAH (0.59) | FAAHTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012068406-A2 | USE OF HEMATOPOIETIC GROWTH FACTOR MIMETICS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2012-05-24 | — | — | WO | disclosed |