SCHEMBL8771937

SCHEMBL8771937

CC(C)[C@@H](C(N)=O)N(C(=O)Oc1ccccc1)C(C)CN(C)c1ccc(F)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.38
ATM Q13315 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
NPY5R Q15761 1/20 0.34
EPHX1 P07099 1/20 0.33
SRD5A1 P18405 1/20 0.33
GPR88 Q9GZN0 2/20 0.33
SCN9A Q15858 1/20 0.33
BCHE P06276 4/20 0.33
ACHE P22303 4/20 0.33
NPC1 O15118 2/20 0.33
ALDH1A1 P00352 2/20 0.33
RAB9A P51151 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
FFAR1 O14842 1/20 0.33
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
MAPT P10636 1/20 0.32
THRB P10828 1/20 0.32
GFER P55789 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8771990 0.91 GPR88 (0.38) TDP1ATML3MBTL1NPY5RSRD5A1
SCHEMBL8772026 0.75 MTNR1A (0.40) TDP1ATML3MBTL1NPY5RBCHE
SCHEMBL8771750 0.72 EPHX1 (0.44) EPHX1GPR88ALDH1A1FFAR1
SCHEMBL8771829 0.72 PSMB5 (0.40) SCN9AALDH1A1MEN1KMT2A
SCHEMBL8771767 0.72 MMP2 (0.44) SCN9AALDH1A1MAPT
SCHEMBL8771901 0.70 MMP2 (0.45) ALDH1A1MAPT
SCHEMBL30847603 0.69 SMN1; SMN2 (0.60) TDP1ATML3MBTL1NPC1ALDH1A1
SCHEMBL8061008 0.68 ALOX5 (0.47) TDP1ATML3MBTL1NPY5RALDH1A1
SCHEMBL8771946 0.68 SLC1A3 (0.40) TDP1BCHEACHEALDH1A1KDM4E
SCHEMBL8771818 0.68 LIPE (0.47) L3MBTL1SCN9ARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648740-B1 AMINO ACID AMIDE DERIVATIVE, AGROHORTICULTURAL BACTERICIDE, AND PRODUCTION PROCESS KUMIAI CHEMICAL INDUSTRY CO (JP) 1997-10-08 EP disclosed