SCHEMBL8772301

SCHEMBL8772301

Cc1cc(Cc2cc(C)c(O)c3cccc(Cc4ccccc4)c23)c2c(Cc3ccccc3)cccc2c1O

nearest known ligand 0.62

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.44
LDHB P07195 1/20 0.44
BCL2 P10415 1/20 0.43
BCL2L1 Q07817 1/20 0.43
LMNA P02545 1/20 0.42
HTT P42858 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8772263 0.82 LMNA (0.53) LDHALDHBBCL2BCL2L1LMNA
SCHEMBL8772393 0.79 PDCD1 (0.46) LMNAHTT
SCHEMBL8772321 0.76 HSP90AA1 (0.42) LMNAHTT
SCHEMBL9854611 0.76 CNR2 (0.43) LDHALDHB
SCHEMBL3725692 0.75 ALDH1A1 (0.52) LDHALDHBBCL2BCL2L1
SCHEMBL30171004 0.75 ALDH1A1 (0.52) LDHALDHBBCL2BCL2L1
SCHEMBL1151311 0.75 HTT (0.61) LMNAHTT
SCHEMBL8772278 0.74 PPARG (0.43) LMNAHTT
SCHEMBL8772361 0.74 KDM4E (0.47) LDHALDHBBCL2BCL2L1LMNA
SCHEMBL27520897 0.74 BCL2 (0.52) LDHALDHBBCL2BCL2L1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0461621-B1 Image forming method CANON KK (JP) 1997-10-15 EP disclosed
EP-0412851-B1 Photosensitive member and multi-color image forming method CANON KK (JP) 1995-06-14 EP disclosed
EP-0363790-B1 Image forming method and image forming medium CANON KK (JP) 1995-05-31 EP disclosed
US-5393638-A Image forming method CANON KABUSHIKI KAISHA (JP) 1995-02-28 US disclosed
US-5374496-A Image forming method CANON KABUSHIKI KAISHA (JP) 1994-12-20 US disclosed
US-5187041-A IMAGE FORMING METHOD AND IMAGE FORMING APPARATUS CANON KABUSHIKI KAISHA (JP) 1993-02-16 US disclosed
US-5171657-A Containing photopolymerizable monomer CANON KABUSHIKI KAISHA (JP) 1992-12-15 US disclosed
EP-0461621-A2 Image forming method CANON KABUSHIKI KAISHA (JP) 1991-12-18 EP disclosed
EP-0453125-A2 Image forming method and image forming apparatus CANON KABUSHIKI KAISHA (JP) 1991-10-23 EP disclosed
US-5021321-A Photothermography; antifogging agents; contrast; lamination of matrix of silver salts and reducing agent and dispersed particles of dye, polymer precursor and photoinitiator CANON KABUSHIKI KAISHA (JP) 1991-06-04 US disclosed