SCHEMBL8772393

SCHEMBL8772393

Cc1cc(Cc2cc(C)c(O)c3cccc(-c4ccccc4)c23)c2c(-c3ccccc3)cccc2c1O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 1/20 0.46
CD274 Q9NZQ7 1/20 0.46
LMNA P02545 1/20 0.42
HTT P42858 1/20 0.42
PKM P14618 1/20 0.40
ESR2 Q92731 1/20 0.40
CDK4 P11802 1/20 0.39
CCND1 P24385 1/20 0.39
KDM4E B2RXH2 2/20 0.37
PTGS1 P23219 1/20 0.37
EGLN1 Q9GZT9 1/20 0.37
SHBG P04278 1/20 0.37
HMGB1 P09429 1/20 0.36
CXCL12 P48061 1/20 0.36
BACE1 P56817 1/20 0.36
MEN1 O00255 1/20 0.36
ALDH1A1 P00352 1/20 0.36
MAPT P10636 1/20 0.36
HPGD P15428 1/20 0.36
MPI P34949 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8772301 0.79 LDHA (0.44) LMNAHTT
SCHEMBL8772321 0.76 HSP90AA1 (0.42) LMNAHTTPKMSHBGMEN1
SCHEMBL1151311 0.75 HTT (0.61) LMNAHTTPKMPTGS1SHBG
SCHEMBL8772278 0.74 PPARG (0.43) LMNAHTTKDM4EPTGS1MEN1
SCHEMBL8772307 0.71 BACE1 (0.48) LMNAHTTPKMESR2HMGB1
SCHEMBL28085880 0.71 ALDH1A1 (0.46) PDCD1CD274CDK4CCND1KDM4E
SCHEMBL8772263 0.69 LMNA (0.53) LMNAHTTPKM
SCHEMBL14176601 0.69 HTT (0.53) LMNAHTTPKMSHBGHMGB1
SCHEMBL172874 0.69 CA1 (0.54) LMNAHTTPKMESR2PTGS1
SCHEMBL31028131 0.69 CA1 (0.54) LMNAHTTPKMESR2PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0461621-B1 Image forming method CANON KK (JP) 1997-10-15 EP disclosed
EP-0412851-B1 Photosensitive member and multi-color image forming method CANON KK (JP) 1995-06-14 EP disclosed
EP-0363790-B1 Image forming method and image forming medium CANON KK (JP) 1995-05-31 EP disclosed
US-5393638-A Image forming method CANON KABUSHIKI KAISHA (JP) 1995-02-28 US disclosed
US-5374496-A Image forming method CANON KABUSHIKI KAISHA (JP) 1994-12-20 US disclosed
US-5187041-A IMAGE FORMING METHOD AND IMAGE FORMING APPARATUS CANON KABUSHIKI KAISHA (JP) 1993-02-16 US disclosed
US-5171657-A Containing photopolymerizable monomer CANON KABUSHIKI KAISHA (JP) 1992-12-15 US disclosed
EP-0461621-A2 Image forming method CANON KABUSHIKI KAISHA (JP) 1991-12-18 EP disclosed
EP-0453125-A2 Image forming method and image forming apparatus CANON KABUSHIKI KAISHA (JP) 1991-10-23 EP disclosed
US-5021321-A Photothermography; antifogging agents; contrast; lamination of matrix of silver salts and reducing agent and dispersed particles of dye, polymer precursor and photoinitiator CANON KABUSHIKI KAISHA (JP) 1991-06-04 US disclosed
EP-0412851-A2 Photosensitive member and multi-color image forming method CANON KABUSHIKI KAISHA (JP) 1991-02-13 EP disclosed