SCHEMBL8772278

SCHEMBL8772278

COc1cccc2c(O)c(C)cc(Cc3cc(C)c(O)c4cccc(OC)c34)c12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 2/20 0.43
RXRA P19793 1/20 0.43
PPARD Q03181 1/20 0.43
PPARA Q07869 1/20 0.43
CALM1 P0DP23 1/20 0.43
ANTXR2 P58335 1/20 0.42
KDM4E B2RXH2 3/20 0.42
LMNA P02545 2/20 0.42
CYP3A4 P08684 2/20 0.42
MAPT P10636 2/20 0.42
ALOX15 P16050 2/20 0.42
ALDH1A1 P00352 1/20 0.42
TP53 P04637 1/20 0.42
HPGD P15428 1/20 0.42
ALOX12 P18054 1/20 0.42
MAPK1 P28482 1/20 0.42
HSD17B10 Q99714 1/20 0.42
NQO1 P15559 1/20 0.41
ALOX5 P09917 2/20 0.40
PTGS2 P35354 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8772321 0.78 HSP90AA1 (0.42) LMNAMAPTALOX15ALDH1A1HPGD
SCHEMBL8772301 0.74 LDHA (0.44) LMNAHTT
SCHEMBL8772393 0.74 PDCD1 (0.46) KDM4ELMNAMAPTALDH1A1HPGD
SCHEMBL8772258 0.73 KDM4E (0.46) CALM1KDM4ELMNAMAPTALOX5
SCHEMBL1151311 0.72 HTT (0.61) LMNAMAPTMAPK1ALOX5PTGS2
SCHEMBL9656300 0.71 MAPT (0.53) PPARGRXRAPPARDPPARAANTXR2
SCHEMBL6572943 0.71 HTT (0.59) KDM4ELMNACYP3A4MAPTALOX15
SCHEMBL14193607 0.69 PDCD1 (0.45) PPARGRXRAPPARDPPARAANTXR2
SCHEMBL9657031 0.69 PPARG (0.47) PPARGRXRAPPARDPPARAANTXR2
SCHEMBL10982267 0.69 ALDH1A1 (0.47) CALM1KDM4ELMNACYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0461621-B1 Image forming method CANON KK (JP) 1997-10-15 EP disclosed
EP-0412851-B1 Photosensitive member and multi-color image forming method CANON KK (JP) 1995-06-14 EP disclosed
EP-0363790-B1 Image forming method and image forming medium CANON KK (JP) 1995-05-31 EP disclosed
US-5393638-A Image forming method CANON KABUSHIKI KAISHA (JP) 1995-02-28 US disclosed
US-5374496-A Image forming method CANON KABUSHIKI KAISHA (JP) 1994-12-20 US disclosed
US-5187041-A IMAGE FORMING METHOD AND IMAGE FORMING APPARATUS CANON KABUSHIKI KAISHA (JP) 1993-02-16 US disclosed
US-5171657-A Containing photopolymerizable monomer CANON KABUSHIKI KAISHA (JP) 1992-12-15 US disclosed
EP-0461621-A2 Image forming method CANON KABUSHIKI KAISHA (JP) 1991-12-18 EP disclosed
EP-0453125-A2 Image forming method and image forming apparatus CANON KABUSHIKI KAISHA (JP) 1991-10-23 EP disclosed
US-5021321-A Photothermography; antifogging agents; contrast; lamination of matrix of silver salts and reducing agent and dispersed particles of dye, polymer precursor and photoinitiator CANON KABUSHIKI KAISHA (JP) 1991-06-04 US disclosed
EP-0412851-A2 Photosensitive member and multi-color image forming method CANON KABUSHIKI KAISHA (JP) 1991-02-13 EP disclosed