SCHEMBL8772305

SCHEMBL8772305

Oc1c(C2CCCCC2)cc(Cc2cc(C3CCCCC3)c(O)c3ccccc23)c2ccccc12

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HMGB1 P09429 1/20 0.45
CXCL12 P48061 1/20 0.45
KDM4E B2RXH2 3/20 0.41
MEN1 O00255 1/20 0.41
MAPT P10636 1/20 0.41
KMT2A Q03164 1/20 0.41
NUDT1 P36639 1/20 0.38
BACE1 P56817 1/20 0.38
PTGDR2 Q9Y5Y4 1/20 0.37
CXCR4 P61073 1/20 0.36
HSD17B10 Q99714 3/20 0.35
ALDH1A1 P00352 2/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
HIF1A Q16665 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
HSP90AA1 P07900 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8772376 0.92 LMNA (0.41) HMGB1CXCL12KDM4EMEN1MAPT
SCHEMBL8772364 0.88 HMGB1 (0.37) HMGB1CXCL12KDM4EMEN1MAPT
SCHEMBL13004817 0.86 KDM4E (0.45) KDM4EMEN1MAPTKMT2ANUDT1
SCHEMBL9644023 0.81 LMNA (0.44) KDM4EMEN1MAPTKMT2ANUDT1
SCHEMBL8772261 0.75 NUDT1 (0.49) NUDT1BACE1HSD17B10ALDH1A1CYP1A2
SCHEMBL9862064 0.73 GAA (0.41) KDM4EMEN1MAPTKMT2ABACE1
SCHEMBL4058553 0.73 PTGDR2 (0.41) KDM4EMEN1MAPTKMT2ANUDT1
SCHEMBL17446312 0.73 KDM4E (0.41) KDM4EMEN1MAPTKMT2ANUDT1
SCHEMBL11553453 0.72 HSD17B10 (0.54) HMGB1CXCL12KDM4EMEN1MAPT
SCHEMBL477417 0.72 PTGDR2 (0.46) MEN1KMT2ANUDT1BACE1PTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0461621-B1 Image forming method CANON KK (JP) 1997-10-15 EP disclosed
EP-0412851-B1 Photosensitive member and multi-color image forming method CANON KK (JP) 1995-06-14 EP disclosed
EP-0363790-B1 Image forming method and image forming medium CANON KK (JP) 1995-05-31 EP disclosed
US-5393638-A Image forming method CANON KABUSHIKI KAISHA (JP) 1995-02-28 US disclosed
US-5374496-A Image forming method CANON KABUSHIKI KAISHA (JP) 1994-12-20 US disclosed
US-5187041-A IMAGE FORMING METHOD AND IMAGE FORMING APPARATUS CANON KABUSHIKI KAISHA (JP) 1993-02-16 US disclosed
US-5171657-A Containing photopolymerizable monomer CANON KABUSHIKI KAISHA (JP) 1992-12-15 US disclosed
EP-0461621-A2 Image forming method CANON KABUSHIKI KAISHA (JP) 1991-12-18 EP disclosed
EP-0453125-A2 Image forming method and image forming apparatus CANON KABUSHIKI KAISHA (JP) 1991-10-23 EP disclosed
US-5021321-A Photothermography; antifogging agents; contrast; lamination of matrix of silver salts and reducing agent and dispersed particles of dye, polymer precursor and photoinitiator CANON KABUSHIKI KAISHA (JP) 1991-06-04 US disclosed
EP-0412851-A2 Photosensitive member and multi-color image forming method CANON KABUSHIKI KAISHA (JP) 1991-02-13 EP disclosed
EP-0363790-A2 Image forming method and image forming medium CANON KABUSHIKI KAISHA (JP) 1990-04-18 EP disclosed