SCHEMBL8772364

SCHEMBL8772364

CC(C)(C)c1cc(Cc2cc(C3CCCCC3)c(O)c3ccccc23)c2ccccc2c1O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HMGB1 P09429 1/20 0.37
CXCL12 P48061 1/20 0.37
HSPA5 P11021 2/20 0.36
CYP2C19 P33261 5/20 0.36
CYP2D6 P10635 4/20 0.36
ALDH1A1 P00352 3/20 0.36
CYP1A2 P05177 3/20 0.36
HSD17B10 Q99714 2/20 0.36
CYP2C9 P11712 3/20 0.35
HIF1A Q16665 2/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
KDM4E B2RXH2 2/20 0.34
MEN1 O00255 1/20 0.34
MAPT P10636 1/20 0.34
KMT2A Q03164 1/20 0.34
TDP1 Q9NUW8 1/20 0.33
TLR7 Q9NYK1 1/20 0.32
PTPN5 P54829 2/20 0.32
PTPN2 P17706 1/20 0.32
BCL2L1 Q07817 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8772305 0.88 HMGB1 (0.45) HMGB1CXCL12CYP2C19CYP2D6ALDH1A1
SCHEMBL8772376 0.83 LMNA (0.41) HMGB1CXCL12CYP2C19CYP2D6ALDH1A1
SCHEMBL8772295 0.82 HSPA5 (0.50) HMGB1CXCL12HSPA5CYP2C19CYP2D6
SCHEMBL13004817 0.76 KDM4E (0.45) CYP2C19CYP2D6ALDH1A1CYP1A2HSD17B10
SCHEMBL8772275 0.76 HSPA5 (0.47) HMGB1CXCL12HSPA5CYP2C19CYP2D6
SCHEMBL9128005 0.73 CA2 (0.42) HMGB1CXCL12HSPA5CYP2C19ALDH1A1
SCHEMBL8772283 0.73 ALDH1A1 (0.45) HSPA5CYP2C19CYP2D6ALDH1A1CYP1A2
SCHEMBL8762782 0.72 HSPA5 (0.46) HMGB1CXCL12HSPA5CYP2C19ALDH1A1
SCHEMBL9644023 0.72 LMNA (0.44) CYP2C19CYP2D6ALDH1A1CYP1A2HSD17B10
SCHEMBL8772290 0.72 KEAP1 (0.45) HMGB1CXCL12HSPA5MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0461621-B1 Image forming method CANON KK (JP) 1997-10-15 EP disclosed
EP-0412851-B1 Photosensitive member and multi-color image forming method CANON KK (JP) 1995-06-14 EP disclosed
EP-0363790-B1 Image forming method and image forming medium CANON KK (JP) 1995-05-31 EP disclosed
US-5393638-A Image forming method CANON KABUSHIKI KAISHA (JP) 1995-02-28 US disclosed
US-5374496-A Image forming method CANON KABUSHIKI KAISHA (JP) 1994-12-20 US disclosed
US-5187041-A IMAGE FORMING METHOD AND IMAGE FORMING APPARATUS CANON KABUSHIKI KAISHA (JP) 1993-02-16 US disclosed
US-5171657-A Containing photopolymerizable monomer CANON KABUSHIKI KAISHA (JP) 1992-12-15 US disclosed
EP-0461621-A2 Image forming method CANON KABUSHIKI KAISHA (JP) 1991-12-18 EP disclosed
EP-0453125-A2 Image forming method and image forming apparatus CANON KABUSHIKI KAISHA (JP) 1991-10-23 EP disclosed
US-5021321-A Photothermography; antifogging agents; contrast; lamination of matrix of silver salts and reducing agent and dispersed particles of dye, polymer precursor and photoinitiator CANON KABUSHIKI KAISHA (JP) 1991-06-04 US disclosed
EP-0363790-A2 Image forming method and image forming medium CANON KABUSHIKI KAISHA (JP) 1990-04-18 EP disclosed