SCHEMBL8772376

SCHEMBL8772376

Cc1cc(Cc2cc(C3CCCCC3)c(O)c3ccccc23)c2ccccc2c1O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.41
HTT P42858 1/20 0.41
PKM P14618 1/20 0.40
HMGB1 P09429 1/20 0.39
CXCL12 P48061 1/20 0.39
KDM4E B2RXH2 3/20 0.36
MAPT P10636 2/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
CYP1A2 P05177 3/20 0.33
CYP2D6 P10635 3/20 0.33
CYP2C19 P33261 3/20 0.33
CYP2C9 P11712 2/20 0.33
NUDT1 P36639 1/20 0.33
BACE1 P56817 1/20 0.33
PTGDR2 Q9Y5Y4 2/20 0.33
ALOX12 P18054 1/20 0.33
PSMB5 P28074 1/20 0.33
CXCR4 P61073 1/20 0.32
ALDH1A1 P00352 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8772305 0.92 HMGB1 (0.45) HMGB1CXCL12KDM4EMAPTMEN1
SCHEMBL8772261 0.84 NUDT1 (0.49) LMNAHTTPKMCYP1A2CYP2D6
SCHEMBL8772364 0.83 HMGB1 (0.37) LMNAHTTHMGB1CXCL12KDM4E
SCHEMBL1151311 0.81 HTT (0.61) LMNAHTTPKMHMGB1CXCL12
SCHEMBL13004817 0.79 KDM4E (0.45) KDM4EMAPTMEN1KMT2ACYP1A2
SCHEMBL14176601 0.75 HTT (0.53) LMNAHTTPKMHMGB1CXCL12
SCHEMBL9644023 0.75 LMNA (0.44) LMNAHTTPKMKDM4EMAPT
SCHEMBL9172537 0.73 HTT (0.56) LMNAHTTPKMHMGB1CXCL12
SCHEMBL9445205 0.73 NUDT1 (0.39) KDM4EMAPTMEN1KMT2ANUDT1
SCHEMBL27584475 0.72 NUDT1 (0.41) LMNAHTTMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0461621-B1 Image forming method CANON KK (JP) 1997-10-15 EP disclosed
EP-0412851-B1 Photosensitive member and multi-color image forming method CANON KK (JP) 1995-06-14 EP disclosed
EP-0363790-B1 Image forming method and image forming medium CANON KK (JP) 1995-05-31 EP disclosed
US-5393638-A Image forming method CANON KABUSHIKI KAISHA (JP) 1995-02-28 US disclosed
US-5374496-A Image forming method CANON KABUSHIKI KAISHA (JP) 1994-12-20 US disclosed
US-5187041-A IMAGE FORMING METHOD AND IMAGE FORMING APPARATUS CANON KABUSHIKI KAISHA (JP) 1993-02-16 US disclosed
US-5171657-A Containing photopolymerizable monomer CANON KABUSHIKI KAISHA (JP) 1992-12-15 US disclosed
EP-0461621-A2 Image forming method CANON KABUSHIKI KAISHA (JP) 1991-12-18 EP disclosed
EP-0453125-A2 Image forming method and image forming apparatus CANON KABUSHIKI KAISHA (JP) 1991-10-23 EP disclosed
US-5021321-A Photothermography; antifogging agents; contrast; lamination of matrix of silver salts and reducing agent and dispersed particles of dye, polymer precursor and photoinitiator CANON KABUSHIKI KAISHA (JP) 1991-06-04 US disclosed
EP-0412851-A2 Photosensitive member and multi-color image forming method CANON KABUSHIKI KAISHA (JP) 1991-02-13 EP disclosed