SCHEMBL8772307

SCHEMBL8772307

Cc1cc(Cc2ccc(O)c(-c3ccccc3)c2)c2ccccc2c1O

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 3/20 0.48
THRA P10827 2/20 0.47
THRB P10828 2/20 0.47
LMNA P02545 1/20 0.45
HTT P42858 1/20 0.45
HSD17B1 P14061 1/20 0.40
HSD17B2 P37059 1/20 0.40
PKM P14618 1/20 0.40
HMGB1 P09429 1/20 0.39
CXCL12 P48061 1/20 0.39
ESR1 P03372 1/20 0.39
ESR2 Q92731 1/20 0.39
PTPN2 P17706 1/20 0.38
PTPN1 P18031 1/20 0.38
PTPN6 P29350 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8772326 0.84 ESR1 (0.58) LMNAHTTPKMHMGB1CXCL12
SCHEMBL8772263 0.81 LMNA (0.53) LMNAHTTPKM
SCHEMBL8772315 0.81 CYP3A4 (0.52) LMNAHTTHSD17B2PKMESR1
SCHEMBL8772359 0.78 LMNA (0.50) LMNAHTTPKMHMGB1CXCL12
SCHEMBL8772373 0.78 LMNA (0.50) LMNAHTTPKMHMGB1CXCL12
SCHEMBL8772267 0.78 LMNA (0.53) LMNAHTTPKMHMGB1CXCL12
SCHEMBL1151311 0.77 HTT (0.61) LMNAHTTPKMHMGB1CXCL12
SCHEMBL1176229 0.77 BACE1 (0.68) BACE1THRATHRBHSD17B1HSD17B2
SCHEMBL30003491 0.77 BACE1 (0.68) BACE1THRATHRBHSD17B1HSD17B2
SCHEMBL2688220 0.74 IDH1 (0.66) BACE1THRATHRBPTPN2PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0461621-B1 Image forming method CANON KK (JP) 1997-10-15 EP disclosed
EP-0412851-B1 Photosensitive member and multi-color image forming method CANON KK (JP) 1995-06-14 EP disclosed
EP-0363790-B1 Image forming method and image forming medium CANON KK (JP) 1995-05-31 EP disclosed
US-5393638-A Image forming method CANON KABUSHIKI KAISHA (JP) 1995-02-28 US disclosed
US-5374496-A Image forming method CANON KABUSHIKI KAISHA (JP) 1994-12-20 US disclosed
US-5187041-A IMAGE FORMING METHOD AND IMAGE FORMING APPARATUS CANON KABUSHIKI KAISHA (JP) 1993-02-16 US disclosed
US-5171657-A Containing photopolymerizable monomer CANON KABUSHIKI KAISHA (JP) 1992-12-15 US disclosed
EP-0461621-A2 Image forming method CANON KABUSHIKI KAISHA (JP) 1991-12-18 EP disclosed
EP-0453125-A2 Image forming method and image forming apparatus CANON KABUSHIKI KAISHA (JP) 1991-10-23 EP disclosed
US-5021321-A Photothermography; antifogging agents; contrast; lamination of matrix of silver salts and reducing agent and dispersed particles of dye, polymer precursor and photoinitiator CANON KABUSHIKI KAISHA (JP) 1991-06-04 US disclosed
EP-0412851-A2 Photosensitive member and multi-color image forming method CANON KABUSHIKI KAISHA (JP) 1991-02-13 EP disclosed
EP-0363790-A2 Image forming method and image forming medium CANON KABUSHIKI KAISHA (JP) 1990-04-18 EP disclosed