Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 2/20 | 0.36 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 2/20 | 0.34 |
| ▸ | CES1 | P23141 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL225939 | 0.98 | TSHR (0.38) | TSHRLTA4HPCSK9PTGS2CES2 | |
| Ammonia Solution, Strong SCHEMBL9771941 | 0.95 | TSHR (0.37) | TSHRLTA4HPCSK9PTGS2CES2 | |
| SCHEMBL7092511 | 0.95 | TSHR (0.37) | TSHRLTA4HPCSK9PTGS2CES2 | |
| SCHEMBL5078343 | 0.95 | TSHR (0.37) | TSHRLTA4HPCSK9PTGS2CES2 | |
| Lithium Ion SCHEMBL503758 | 0.95 | TSHR (0.37) | TSHRLTA4HPCSK9PTGS2CES2 | |
| Ammonia Solution, Strong SCHEMBL8571366 | 0.93 | TSHR (0.36) | TSHRLTA4HPCSK9PTGS2CES2 | |
| Tetramethylammonium Ion SCHEMBL1276928 | 0.91 | DNM1 (0.39) | TSHRLTA4HPCSK9PTGS2CES2 | |
| SCHEMBL8567042 | 0.91 | SIGMAR1 (0.36) | TSHRLTA4HPCSK9PTGS2CES2 | |
| SCHEMBL8756194 | 0.91 | TSHR (0.35) | TSHRLTA4HPCSK9PTGS2CES2 | |
| SCHEMBL4532567 | 0.91 | LTA4H (0.38) | TSHRLTA4HPCSK9CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0387087-B1 | Photoinitiator compositions, photohardenable compositions and photosensitive microcapsules | CYCOLOR INC (US) | 1997-10-08 | — | — | EP | disclosed |
| US-5230982-A | Heterocyclic disulfides for crosslinking | THE MEAD CORPORATION (US) | 1993-07-27 | — | — | US | disclosed |
| EP-0387087-A2 | Photoinitiator compositions, photohardenable compositions and photosensitive microcapsules | THE MEAD CORPORATION (US) | 1990-09-12 | — | — | EP | disclosed |