SCHEMBL8772344

SCHEMBL8772344

BCCCC(c1ccccc1)(c1ccccc1)c1ccccc1.c1ccc(C[B-](c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 14/20 0.43
KCNH2 Q12809 2/20 0.35
CYP2C9 P11712 2/20 0.35
CYP2C19 P33261 2/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL532850 0.81 KIF11 (0.61) KIF11KCNH2CYP2C9CYP2C19CYP3A4
Ammonia Solution, Strong SCHEMBL4606388 0.79 KIF11 (0.59) KIF11KCNH2CYP2C9CYP2C19CYP3A4
SCHEMBL15051981 0.79 KIF11 (0.59) KIF11KCNH2CYP2C9CYP2C19CYP3A4
Water SCHEMBL28757871 0.79 KIF11 (0.59) KIF11KCNH2CYP2C9CYP2C19CYP3A4
SCHEMBL307003 0.75 CALM1 (0.43)
SCHEMBL810137 0.74 KIF11 (0.57) KIF11KCNH2CYP2C9CYP2C19CYP3A4
Lithium Ion SCHEMBL8757501 0.73 CALM1 (0.41)
Ammonia Solution, Strong SCHEMBL15569691 0.73 CALM1 (0.41)
SCHEMBL17417857 0.73 CALM1 (0.41)
SCHEMBL8365385 0.70 SIGMAR1 (0.50) KIF11KCNH2CYP2C9CYP2C19CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0387087-B1 Photoinitiator compositions, photohardenable compositions and photosensitive microcapsules CYCOLOR INC (US) 1997-10-08 EP disclosed
US-5230982-A Heterocyclic disulfides for crosslinking THE MEAD CORPORATION (US) 1993-07-27 US disclosed
EP-0387087-A2 Photoinitiator compositions, photohardenable compositions and photosensitive microcapsules THE MEAD CORPORATION (US) 1990-09-12 EP disclosed