Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CCR3 | P51677 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.36 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.36 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8439618 | 0.93 | GSK3A (0.43) | GSK3AGSK3BSIGMAR1TDP1L3MBTL1 | |
| SCHEMBL8772475 | 0.92 | FAAH (0.42) | GSK3AGSK3BSIGMAR1TDP1L3MBTL1 | |
| SCHEMBL8772402 | 0.89 | HTR2A (0.43) | GSK3AGSK3BSIGMAR1MEN1CYP1A2 | |
| SCHEMBL8772495 | 0.88 | GSK3A (0.41) | GSK3AGSK3BSIGMAR1L3MBTL1MEN1 | |
| SCHEMBL8619484 | 0.87 | GSK3B (0.39) | GSK3AGSK3BSIGMAR1TDP1L3MBTL1 | |
| SCHEMBL8440707 | 0.83 | HSP90AA1 (0.45) | MEN1KMT2ATSHRPLAAT3PLAAT5 | |
| SCHEMBL8772523 | 0.83 | HCRTR1 (0.43) | GSK3AGSK3BL3MBTL1MGLLMEN1 | |
| SCHEMBL8555803 | 0.83 | HRH3 (0.41) | SIGMAR1 | |
| SCHEMBL8549722 | 0.80 | HRH3 (0.41) | SIGMAR1CCR3 | |
| SCHEMBL8553197 | 0.80 | HTR2A (0.40) | SIGMAR1TDP1MEN1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799200-A1 | SUBSTITUTED AZETIDIN-2-ONES FOR TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 1997-10-08 | — | — | EP | disclosed |