Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8439618 | 0.93 | GSK3A (0.43) | CYP1A2CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL8772475 | 0.92 | FAAH (0.42) | CYP1A2CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL8553197 | 0.91 | HTR2A (0.40) | HTR2AKDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8772398 | 0.89 | GSK3A (0.39) | CYP1A2CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL8772495 | 0.88 | GSK3A (0.41) | HTR2AMEN1KMT2AGSK3AGSK3B | |
| SCHEMBL8772498 | 0.87 | HTT (0.39) | MEN1KMT2AALDH1A1GAA | |
| SCHEMBL8619484 | 0.87 | GSK3B (0.39) | CYP1A2CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL8443653 | 0.83 | KMT2A (0.46) | KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL8772523 | 0.83 | HCRTR1 (0.43) | MEN1KMT2AGSK3AGSK3BALDH1A1 | |
| SCHEMBL8555803 | 0.83 | HRH3 (0.41) | DRD2DRD3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799200-A1 | SUBSTITUTED AZETIDIN-2-ONES FOR TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 1997-10-08 | — | — | EP | disclosed |