Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | SNCA | P37840 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.42 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.42 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9018903 | 0.86 | TSHR (0.50) | TSHRPTPN1SNCAALDH1A1MAOB | |
| SCHEMBL24230227 | 0.84 | TSHR (0.67) | TSHRPTPN1ALDH1A1TAS2R14PLA2G10 | |
| SCHEMBL1319907 | 0.77 | LMNA (0.64) | TSHRALDH1A1PLA2G10PLA2G2ALMNA | |
| SCHEMBL1290930 | 0.77 | KMT2A (0.58) | TSHRALDH1A1ALOX15PLA2G10PLA2G2A | |
| SCHEMBL27902405 | 0.76 | KEAP1 (0.64) | ALDH1A1MAOBKDM4EMEN1MAPK1 | |
| SCHEMBL2564249 | 0.75 | TAAR1 (0.46) | ALDH1A1MAOBGAASMN1; SMN2 | |
| SCHEMBL3306954 | 0.75 | HTR2A (0.56) | PTPN1ALDH1A1LMNAKDM4EKMT2A | |
| SCHEMBL9421738 | 0.73 | ALDH1A1 (0.64) | TSHRALDH1A1ALOX15LMNAKDM4E | |
| SCHEMBL780161 | 0.72 | CA1 (0.47) | TSHRPTPN1ALDH1A1TAS2R14LMNA | |
| SCHEMBL9440186 | 0.72 | TAAR1 (0.43) | PTPN1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639559-B1 | Preparation of 1,2-diacyl-2-(t-alkyl)hydrazines | ROHM & HAAS (US) | 1997-10-15 | — | — | EP | claimed |
| EP-0639559-A1 | Preparation of 1,2-diacyl-2-(t-alkyl)hydrazines | ROHM AND HAAS COMPANY (US) | 1995-02-22 | — | — | EP | claimed |
| CN-1050599-C | Preparation of 1,2-diacyl-2-(T-alkyl) hydrazines | ROHM & HAAS (US) | 2000-03-22 | — | — | CN | disclosed |
| EP-0639559-B1 | Preparation of 1,2-diacyl-2-(t-alkyl)hydrazines | ROHM & HAAS (US) | 1997-10-15 | — | — | EP | disclosed |
| CN-1109049-A | Preparation of 1,2-diacyl-2-(T-alkyl) hydrazines | ROHM & HAAS (US) | 1995-09-27 | — | — | CN | disclosed |
| EP-0639559-A1 | Preparation of 1,2-diacyl-2-(t-alkyl)hydrazines | ROHM AND HAAS COMPANY (US) | 1995-02-22 | — | — | EP | disclosed |