Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | VNN1 | O95497 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.44 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.44 |
| ▸ | SNCA | P37840 | 1/20 | 0.44 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.43 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24230227 | 0.87 | TSHR (0.67) | TSHRPTPN1SRD5A2TAS2R14PLA2G10 | |
| SCHEMBL8772406 | 0.86 | TSHR (0.47) | TSHRPTPN1NPC1RAB9AGAA | |
| SCHEMBL7895926 | 0.80 | ACHE (0.51) | TSHRPTPN1NPC1RAB9ASRD5A2 | |
| SCHEMBL27902405 | 0.79 | KEAP1 (0.64) | GAAMAOBALDH1A1KDM4E | |
| SCHEMBL2564249 | 0.78 | TAAR1 (0.46) | GAAMAOBALDH1A1 | |
| SCHEMBL11464000 | 0.78 | TSHR (0.50) | TSHRNPC1RAB9AMAOBSRD5A2 | |
| SCHEMBL26134815 | 0.78 | TSHR (0.69) | TSHRGAASRD5A2PLA2G10PLA2G2A | |
| SCHEMBL3306954 | 0.78 | HTR2A (0.56) | PTPN1LMNAALDH1A1KDM4E | |
| SCHEMBL8094666 | 0.76 | ALDH1A1 (0.67) | NPC1RAB9ASRD5A2PLA2G10PLA2G2A | |
| SCHEMBL1247035 | 0.76 | PLA2G10 (0.69) | TSHRSRD5A2PLA2G10PLA2G2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543573-A | INSECTICIDES | NIHON NOHYAKU CO., LTD. (JP) | 1996-08-06 | — | — | US | disclosed |
| EP-0462456-B1 | Hydrazinecarboxamide derivatives, a process for production thereof, and uses thereof | NIHON NOHYAKU CO LTD (JP) | 1996-05-08 | — | — | EP | disclosed |
| EP-0462456-A1 | Hydrazinecarboxamide derivatives, a process for production thereof, and uses thereof | NIHON NOHYAKU CO., LTD. (JP) | 1991-12-27 | — | — | EP | disclosed |