Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8441250 | 0.80 | ACE (0.37) | ACEKDM4ENPSR1 | |
| SCHEMBL10367995 | 0.66 | ACE (0.60) | ACE | |
| SCHEMBL5547511 | 0.62 | ACE (0.31) | ACEKDM4E | |
| SCHEMBL8104141 | 0.60 | KDM4E (0.35) | ACEKDM4ENPSR1 | |
| SCHEMBL18106803 | 0.59 | L3MBTL1 (0.43) | ACEKDM4ENPSR1 | |
| SCHEMBL11621452 | 0.56 | ACE (0.40) | ACE | |
| SCHEMBL8808741 | 0.56 | — | — | |
| SCHEMBL10371338 | 0.54 | ACE (0.64) | ACE | |
| SCHEMBL24773837 | 0.51 | CA12 (0.50) | KDM4E | |
| SCHEMBL435819 | 0.50 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799200-A1 | SUBSTITUTED AZETIDIN-2-ONES FOR TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 1997-10-08 | — | — | EP | disclosed |