Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8772552 | 0.90 | KMT2A (0.41) | KMT2AALDH1A1GAAKCNA5KCNH2 | |
| SCHEMBL8772402 | 0.87 | HTR2A (0.43) | MEN1KMT2AALDH1A1GAA | |
| SCHEMBL8443006 | 0.84 | POLB (0.41) | HTTALDH1A1POLB | |
| SCHEMBL8553197 | 0.81 | HTR2A (0.40) | HTTMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL8439618 | 0.80 | GSK3A (0.43) | MEN1KMT2ATP53 | |
| SCHEMBL8772475 | 0.79 | FAAH (0.42) | MEN1KMT2ATP53 | |
| SCHEMBL8772509 | 0.77 | TSHR (0.44) | MEN1KMT2AALDH1A1POLBMAPT | |
| SCHEMBL8772398 | 0.77 | GSK3A (0.39) | HTTMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL8772533 | 0.76 | KCNA5 (0.42) | HTTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL8554624 | 0.76 | MAPT (0.39) | HTTMEN1KMT2AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799200-A1 | SUBSTITUTED AZETIDIN-2-ONES FOR TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 1997-10-08 | — | — | EP | claimed |