Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 18/20 | 0.61 |
| ▸ | RARA | P10276 | 17/20 | 0.61 |
| ▸ | RARG | P13631 | 17/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8772626 | 0.94 | RARA (0.62) | RARBRARARARG | |
| SCHEMBL5480486 | 0.92 | RARB (0.73) | RARBRARARARG | |
| SCHEMBL7642585 | 0.84 | RARB (0.84) | RARBRARARARG | |
| SCHEMBL8772741 | 0.81 | RARA (0.53) | RARBRARARARG | |
| SCHEMBL8772769 | 0.81 | RARA (0.45) | RARBRARARARG | |
| SCHEMBL7633676 | 0.80 | RARA (0.83) | RARBRARARARG | |
| SCHEMBL8328655 | 0.79 | RARB (0.52) | RARBRARARARG | |
| SCHEMBL4500885 | 0.78 | RARB (0.53) | RARBRARARARG | |
| SCHEMBL4506168 | 0.77 | RARB (0.57) | RARBRARARARG | |
| SCHEMBL4510587 | 0.77 | RARB (0.52) | RARBRARARARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0800517-A1 | ACETYLENES DISUBSTITUTED WITH A 5 OR 8 SUBSTITUTED TETRAHYDRONAPHTHYL OR DIHYDRONAPHTHYL GROUP AND WITH AN ARYL OR HETEROARYL GROUPS HAVING RETINOID-LIKE BIOLOGICAL ACTIVITY | Allergan (US) | 1997-10-15 | — | — | EP | disclosed |