Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | RAD52 | P43351 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GPR3 | P46089 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2493164 | 0.78 | PARP1 (0.43) | ALDH1A1KDM4EGAALMNAHPGD | |
| SCHEMBL10396514 | 0.77 | ATM (0.46) | ALDH1A1KDM4EGAALMNAHPGD | |
| SCHEMBL5044710 | 0.76 | ELANE (0.41) | ALDH1A1KDM4EGAAPOLBGLA | |
| SCHEMBL11919171 | 0.76 | PTGS1 (0.46) | ALDH1A1KDM4EGAAPOLBRAD52 | |
| SCHEMBL7002086 | 0.76 | LOXL2 (0.42) | ALDH1A1KDM4EGAAPOLBRAD52 | |
| SCHEMBL2490785 | 0.75 | LMNA (0.47) | ALDH1A1KDM4EGAALMNAHPGD | |
| SCHEMBL2492592 | 0.75 | LMNA (0.47) | ALDH1A1KDM4EGAALMNAHPGD | |
| SCHEMBL1027461 | 0.74 | SMN1; SMN2 (0.43) | ALDH1A1KDM4EGAAPOLBGLA | |
| SCHEMBL3229873 | 0.74 | LMNA (0.40) | ALDH1A1KDM4EGAAPOLBLMNA | |
| SCHEMBL7155004 | 0.73 | ALDH1A1 (0.40) | ALDH1A1KDM4EPOLBGLAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0789692-A1 | BENZISOXAZOLE DERIVATIVES AND PESTICIDAL COMPOSITIONS CONTAINING THEM | Novartis AG (CH) | 1997-08-20 | — | — | EP | disclosed |