Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18264144 | 0.88 | GAA (0.45) | CYP2D6MAPTKMT2AMEN1LMNA | |
| SCHEMBL3172941 | 0.80 | MAPT (0.55) | CYP2D6MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL5733939 | 0.80 | CYP2D6 (0.43) | CYP2D6MAPTRXFP1LMNARAB9A | |
| SCHEMBL23130630 | 0.78 | METAP2 (0.44) | CYP2D6MAPTSMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL3178648 | 0.76 | ALDH1A1 (0.49) | POLBL3MBTL1KMT2ALMNARAB9A | |
| SCHEMBL25969601 | 0.75 | MAPT (0.61) | MAPTKMT2ALMNACYP1A2CYP3A4 | |
| SCHEMBL512464 | 0.75 | CASP1 (0.44) | MAPTPOLBRXFP1SMN1; SMN2L3MBTL1 | |
| SCHEMBL2242408 | 0.74 | MAPT (0.46) | PGRMAPTPOLBSMN1; SMN2L3MBTL1 | |
| SCHEMBL9319668 | 0.74 | PTPN22 (0.50) | CYP2D6MAPTTTRCYP1A2CYP2C9 | |
| SCHEMBL155578 | 0.74 | CYP2D6 (0.44) | CYP2D6MAPTSMN1; SMN2LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0348006-B2 | Liquid transport device and diagnostic assay device | BEHRING DIAGNOSTICS INC (US) | 1997-10-22 | — | — | EP | disclosed |
| US-5102786-A | Phenoxy-substituted naphthalene compounds and salts as blocking and/or displacing agent; accuracy, duplication | PB DIAGNOSTIC SYSTEMS, INC. (US) | 1992-04-07 | — | — | US | disclosed |
| US-5051237-A | Chemical diagnosis system | P B DIAGNOSTIC SYSTEMS, INC. (US) | 1991-09-24 | — | — | US | disclosed |
| EP-0348006-A2 | Liquid transport device and diagnostic assay device | BEHRING DIAGNOSTICS INC. (US) | 1989-12-27 | — | — | EP | disclosed |
| EP-0293971-A1 | Biological diagnostic assay system | PB Diagnostic Systems, Inc. (US) | 1988-12-07 | — | — | EP | disclosed |
| WO-1988009505-A1 | BIOLOGICAL DIAGNOSTIC ASSAY SYSTEM | P B DIAGNOSTIC SYSTEMS, INC. (US) | 1988-12-01 | — | — | WO | disclosed |