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Sugi Predict / Compounds / Naphthalene

Naphthalene

Naphthalene

SCHEMBL8773080

O=S(=O)(O)Cl.c1ccc2ccccc2c1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP2A6 P11509 2/20 0.50
▸ ALOX12 P18054 2/20 0.50
▸ ALDH1A1 P00352 1/20 0.46
▸ HSD17B10 Q99714 1/20 0.46
▸ TDP1 Q9NUW8 1/20 0.46
▸ TSHR P16473 1/20 0.46
▸ SMN1; SMN2 Q16637 1/20 0.46
▸ LMNA P02545 1/20 0.41
▸ CES2 O00748 1/20 0.39
▸ CES1 P23141 1/20 0.39
▸ CA1 P00915 3/20 0.38
▸ CA2 P00918 3/20 0.38
▸ CA9 Q16790 2/20 0.38
▸ F2 P00734 1/20 0.38
▸ PRSS1 P07477 1/20 0.38
▸ PRSS2 P07478 1/20 0.38
▸ PRSS3 P35030 1/20 0.38
▸ CYP1A2 P05177 1/20 0.38
▸ L3MBTL1 Q9Y468 2/20 0.37
▸ HTR6 P50406 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Naphthalene SCHEMBL2678900 0.87 ALOX12 (0.57) CYP2A6ALOX12ALDH1A1TSHRSMN1; SMN2
Naphthalene SCHEMBL672294 0.87 ALOX12 (0.57) CYP2A6ALOX12ALDH1A1TSHRSMN1; SMN2
Naphthalene SCHEMBL260764 0.87 CYP2A6 (0.57) CYP2A6ALOX12ALDH1A1HSD17B10TDP1
Naphthalene SCHEMBL29361795 0.87 ALOX12 (0.57) CYP2A6ALOX12ALDH1A1TSHRSMN1; SMN2
Naphthalene SCHEMBL5574575 0.87 ALOX12 (0.57) CYP2A6ALOX12ALDH1A1TSHRSMN1; SMN2
Naphthalene SCHEMBL28674544 0.87 ALOX12 (0.57) CYP2A6ALOX12ALDH1A1TSHRSMN1; SMN2
Naphthalene SCHEMBL5493887 0.84 CYP2A6 (0.53) CYP2A6ALOX12ALDH1A1HSD17B10TDP1
Naphthalene SCHEMBL9484717 0.84 ALOX12 (0.53) CYP2A6ALOX12ALDH1A1TSHRSMN1; SMN2
Naphthalene SCHEMBL8773082 0.84 ALOX12 (0.53) CYP2A6ALOX12ALDH1A1TSHRSMN1; SMN2
Naphthalene SCHEMBL28279517 0.84 CYP2A6 (0.53) CYP2A6ALOX12ALDH1A1HSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0439585-B1 IMMOBILISATION OF LIGANDS BY RADIO-DERIVATIZED POLYMERS MAG GEORG MAYRHOFER & CO OHG (AT) 1997-10-29 — — EP disclosed
US-5196478-A Polystyrene, assays EPIPHARM ALLERGIE-SERVICE GESELLSCHAFT M.B.H. (AT) 1993-03-23 — — US disclosed
EP-0439585-A1 IMMOBILISATION OF LIGANDS BY RADIO-DERIVATIZED POLYMERS. EPIPHARM ALLERGIE SERVICE (AT) 1991-08-07 — — EP disclosed
WO-1991002768-A1 IMMOBILISATION OF LIGANDS BY RADIO-DERIVATIZED POLYMERS EPIPHARM ALLERGIE-SERVICE GESELLSCHAFT M.B.H. (AT) 1991-03-07 — — WO disclosed
US-4415603-A HIGH-SPEED ULTRAVIOLET RADIATION POLYMERIZATION OF AN ACRYLATE, UNSATURATED MONOMERS, PHOTOINITIATOR, PEROXIDE AND REDUCING SALT COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 1983-11-15 — — US disclosed
US-4295948-A Photocurable adhesive from acrylic acid, acrylamide, dimethylaminoethyl methacrylate, benzophenone and methyl ethyl ketone BATTELLE MEMORIAL INSTITUTE (CH) 1981-10-20 — — US disclosed
US-4230766-A ULTRAVIOLET-RADIATION POLYMERIZATION AND CROSSLINKING OF A MIXTURE OF ACRYLIC-MODIFIED EPOXY RESINS AND ACRYLIC MONOMERS COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 1980-10-28 — — US disclosed
US-4118366-A Compositions for the production of opaque coatings by radiation BASF FARBEN & FASERN AG (DE) 1978-10-03 — — US disclosed
US-3984584-A Opaque coatings and films produced by the hardening of synthetic resins with light BASF FARBEN & FASERN AKTIENGESELLSCHAFT 1976-10-05 — — US disclosed
US-3933875-A Opaque polyester copolymer coated articles BASF FARBEN & FASERN AG (DT) 1976-01-20 — — US disclosed
US-3932419-A QUINOLINE DYES BAYER AKTIENGESELLSCHAFT (DT) 1976-01-13 — — US disclosed