Sugi Predict

Sugi Predict / Compounds / Naphthalene

Naphthalene

Naphthalene

SCHEMBL260764

O=S(=O)(Cl)Cl.c1ccc2ccccc2c1

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP2A6 P11509 3/20 0.57
▸ ALOX12 P18054 1/20 0.57
▸ ALDH1A1 P00352 2/20 0.50
▸ HSD17B10 Q99714 2/20 0.50
▸ TDP1 Q9NUW8 2/20 0.50
▸ LMNA P02545 2/20 0.44
▸ CA1 P00915 5/20 0.41
▸ CA2 P00918 5/20 0.41
▸ CA9 Q16790 4/20 0.41
▸ HTR6 P50406 1/20 0.40
▸ L3MBTL1 Q9Y468 1/20 0.39
▸ PAX8 Q06710 1/20 0.38
▸ TSHR P16473 2/20 0.37
▸ MEN1 O00255 1/20 0.37
▸ CDC25B P30305 1/20 0.37
▸ KMT2A Q03164 1/20 0.37
▸ SMN1; SMN2 Q16637 2/20 0.37
▸ IDO1 P14902 1/20 0.36
▸ DNMT1 P26358 1/20 0.36
▸ DNMT3L Q9UJW3 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Naphthalene SCHEMBL28261827 0.97 ALDH1A1 (0.55) CYP2A6ALOX12ALDH1A1HSD17B10TDP1
Naphthalene SCHEMBL28279517 0.97 CYP2A6 (0.53) CYP2A6ALOX12ALDH1A1HSD17B10TDP1
Naphthalene SCHEMBL5493887 0.97 CYP2A6 (0.53) CYP2A6ALOX12ALDH1A1HSD17B10TDP1
Naphthalene SCHEMBL8773080 0.87 CYP2A6 (0.50) CYP2A6ALOX12ALDH1A1HSD17B10TDP1
Anthracene SCHEMBL2339557 0.87 LMNA (0.46) CYP2A6ALOX12ALDH1A1HSD17B10TDP1
Naphthalene SCHEMBL28256422 0.84 CYP2A6 (0.40) CYP2A6ALOX12ALDH1A1HSD17B10TDP1
Naphthalene SCHEMBL11140693 0.80 CYP2A6 (0.42) CYP2A6ALOX12ALDH1A1HSD17B10TDP1
Naphthalene SCHEMBL6683058 0.80 ALDH1A1 (0.84) CYP2A6ALOX12ALDH1A1HSD17B10TDP1
Naphthalene SCHEMBL29361795 0.79 ALOX12 (0.57) CYP2A6ALOX12ALDH1A1LMNACA1
Naphthalene SCHEMBL5574575 0.79 ALOX12 (0.57) CYP2A6ALOX12ALDH1A1LMNACA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 470 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117843590-A 3-amino-4- (piperazin-1-yl) benzamide derivative, pharmaceutical composition containing same, and preparation method and application thereof 中国药科大学 2024-04-09 — — CN claimed
CN-110105255-B Mild synthesis method of diaryl thioether 江西理工大学 2020-11-03 — — CN claimed
CN-110105255-A A kind of synthetic method of mild diaryl sulfide 江西理工大学 2019-08-09 — — CN claimed
CN-109456230-A A kind of preparation method of photosensitizer 大晶信息化学品（徐州）有限公司 2019-03-12 — — CN claimed
CN-109293535-A A kind of preparation method of 215 naphthalene sulfonyl chloride 大晶信息化学品（徐州）有限公司 2019-02-01 — — CN claimed
CN-109265378-A A method of concentration purification 215 naphthalene sulfonyl chloride of crude product 大晶信息化学品（徐州）有限公司 2019-01-25 — — CN claimed
US-10018853-B2 Methods of altering the refractive index of materials BATTELLE MEMORIAL INSTITUTE (US) 2018-07-10 — — US claimed
CN-105921029-A Technology for preparing composite nanofiltration membrane for water treatment 安徽国能亿盛环保科技有限公司 2016-09-07 — — CN claimed
US-20160195734-A1 METHODS OF ALTERING THE REFRACTIVE INDEX OF MATERIALS BATTELLE MEMORIAL INSTITUTE 2016-07-07 — — US claimed
WO-2015038614-A1 METHODS OF ALTERING THE REFRACTIVE INDEX OF MATERIALS BATTELLE MEMORIAL INSTITUTE (US) 2015-03-19 — — WO claimed
CN-101738856-B Heat-sensible composition for positive thermosensitive CTP plate without preheating and plate-making method by using same GUANGXI YULIN JINLONG PS PLATE PRINTING MATERIAL CO LTD 2012-11-07 — — CN claimed
EP-2504000-A1 TRANSCRIPTION FACTOR INHIBITORS AND RELATED COMPOSITIONS, FORMULATIONS AND METHODS The Ohio State University (US) 2012-10-03 — — EP claimed
US-20110212911-A1 TRANSCRIPTION FACTOR INHIBITORS AND RELATED COMPOSITIONS, FORMULATIONS AND METHODS NIH - DEITR 2011-09-01 — — US claimed
WO-2011066263-A1 TRANSCRIPTION FACTOR INHIBITORS AND RELATED COMPOSITIONS, FORMULATIONS AND METHODS THE OHIO STATE UNIVERSITY (US) 2011-06-03 — — WO claimed
CN-101738856-A Sensible heat composition for positive thermosensitive CTP plate without preheating and plate-making method by using same GUANGXI YULIN JINLONG PS PLATE 2010-06-16 — — CN claimed
US-20070263060-A1 Hybrid Energy Curable Solvent-Based Liquid Printing Inks SUN CHEMICAL CORPORATION 2007-11-15 — — US claimed
WO-2005071027-A1 HYBRID ENERGY CURABLE SOLVENT-BASED LIQUID PRINTING INKS SUN CHEMICAL CORPORATION (US) 2005-08-04 — — WO claimed
CN-1442695-A Fluorescence diagnostic reagent for gastric cancer LI LI (CN) 2003-09-17 — — CN claimed
US-4538252-A Light induced capacitance changes in donor polymers (or small molecules) films and its use for information storage in video disks and the like INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1985-08-27 — — US claimed
EP-0073304-A1 A method of storing data in a storage device International Business Machines Corporation (US) 1983-03-09 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110212911-A1 TRANSCRIPTION FACTOR INHIBITORS AND RELATED COMPOSITIONS, FORMULATIONS AND METHODS STAT3, TCF12, STAT5A CYP2A6 4369/4885ALOX12 698/4885ALDH1A1 3193/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.