Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.50 |
| ▸ | ME2 | P23368 | 1/20 | 0.49 |
| ▸ | ME1 | P48163 | 1/20 | 0.49 |
| ▸ | ME3 | Q16798 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PLEC | Q15149 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1,6-Hexanediol SCHEMBL11778711 | 0.87 | POLB (0.49) | POLBGPR35ME2ME1ME3 | |
| SCHEMBL11785649 | 0.85 | MEN1 (0.54) | POLBME2ME1ME3ALDH1A1 | |
| Phosphoric Acid SCHEMBL9602526 | 0.82 | MEN1 (0.50) | POLBALDH1A1MEN1KMT2AHTT | |
| SCHEMBL9678351 | 0.81 | MEN1 (0.51) | POLBALDH1A1MEN1KMT2AHTT | |
| SCHEMBL5380957 | 0.79 | ME2 (0.70) | POLBGPR35ME2ME1ME3 | |
| SCHEMBL16131299 | 0.79 | MEN1 (0.60) | POLBALDH1A1MEN1KMT2AHTT | |
| SCHEMBL7673493 | 0.77 | MEN1 (0.54) | POLBALDH1A1MEN1KMT2AHTT | |
| SCHEMBL10877627 | 0.77 | MEN1 (0.54) | POLBALDH1A1MEN1KMT2AHTT | |
| SCHEMBL30761918 | 0.77 | WDR5 (0.54) | POLBALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL23139694 | 0.76 | MEN1 (0.56) | POLBALDH1A1MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150024403-A1 | METHOD FOR DETECTING REPLICATION OR COLONIZATION OF A BIOLOGICAL THERAPEUTIC | GENELUX CORPORATION | 2015-01-22 | — | — | US | disclosed |
| US-8859256-B2 | Method for detecting replication or colonization of a biological therapeutic | GENELUX CORPORATION (US) | 2014-10-14 | — | — | US | disclosed |
| EP-2764119-A2 | METHOD FOR DETECTING REPLICATION OR COLONIZATION OF A BIOLOGICAL THERAPEUTIC | Genelux Corporation (US) | 2014-08-13 | — | — | EP | disclosed |
| US-20130130292-A1 | Method for detecting replication or colonization of a biological therapeutic | GENELUX CORPORATION | 2013-05-23 | — | — | US | disclosed |
| WO-2013052915-A2 | METHOD FOR DETECTING REPLICATION OR COLONIZATION OF A BIOLOGICAL THERAPEUTIC | GENELUX CORPORATION (US) | 2013-04-11 | — | — | WO | disclosed |
| EP-0424465-B1 | PREPARATION AND USE OF FLUORESCENT BENZOTHIAZOLE DERIVATIVES | JBL SCIENT INC (US) | 1997-10-29 | — | — | EP | disclosed |
| US-5424440-A | A non-fluorescent detector when hydrolyzing with selected enzyme become fluorescent; colorimetric analysis, spectrophotometry | JBL SCIENTIFIC, INC. (US) | 1995-06-13 | — | — | US | disclosed |
| EP-0424465-A4 | PREPARATION AND USE OF FLUORESCENT BENZOTHIAZOLE DERIVATIVES | — | 1991-07-03 | — | — | EP | disclosed |
| EP-0424465-A1 | PREPARATION AND USE OF FLUORESCENT BENZOTHIAZOLE DERIVATIVES. | JBL SCIENT INC (US) | 1991-05-02 | — | — | EP | disclosed |
| WO-1990000618-A1 | PREPARATION AND USE OF FLUORESCENT BENZOTHIAZOLE DERIVATIVES | JBL SCIENTIFIC, INC. (US) | 1990-01-25 | — | — | WO | disclosed |