Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.44 |
| ▸ | SCD | O00767 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8381667 | 0.85 | MAOB (0.46) | CA2MAPTMAOAMAOBHSD17B1 | |
| SCHEMBL3086399 | 0.84 | MAPT (0.61) | MAPTMAOAMAOBHSD17B1HSD17B2 | |
| SCHEMBL8773258 | 0.79 | MAPT (0.43) | CA2MAPTMAOAMAOBHSD17B1 | |
| SCHEMBL4638895 | 0.77 | KMT2A (0.64) | CA2MAPTNPC1RAB9ACYP3A4 | |
| SCHEMBL8773253 | 0.75 | CA2 (0.46) | CA2MAPTSCDNPC1RAB9A | |
| SCHEMBL3086757 | 0.75 | NPC1 (0.63) | CA2MAPTHSD17B1HSD17B2NPC1 | |
| SCHEMBL3093869 | 0.73 | RAB9A (0.57) | MAPTMAOBNPC1RAB9AMEN1 | |
| SCHEMBL8031699 | 0.72 | MAPT (0.49) | CA2MAPTNPC1RAB9ACYP1A2 | |
| Phosphoric Acid SCHEMBL8381672 | 0.72 | HSD17B1 (0.57) | CA2MAPTMAOBHSD17B1HSD17B2 | |
| SCHEMBL2762136 | 0.72 | MAPT (0.67) | MAPTMAOAMAOBHSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0424465-B1 | PREPARATION AND USE OF FLUORESCENT BENZOTHIAZOLE DERIVATIVES | JBL SCIENT INC (US) | 1997-10-29 | — | — | EP | disclosed |
| US-5424440-A | A non-fluorescent detector when hydrolyzing with selected enzyme become fluorescent; colorimetric analysis, spectrophotometry | JBL SCIENTIFIC, INC. (US) | 1995-06-13 | — | — | US | disclosed |