SCHEMBL8773329

SCHEMBL8773329

CCCN1CCN(CCC)C(=O)N(CCC)CC1

nearest known ligand 0.47

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.47
NPC1 O15118 3/20 0.43
RAB9A P51151 1/20 0.43
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
DRD2 P14416 9/20 0.42
SIGMAR1 Q99720 2/20 0.42
RECQL P46063 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.38
DRD3 P35462 3/20 0.37
KCNH2 Q12809 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL609688 0.91 L3MBTL1 (0.42) POLBNPC1RAB9AMEN1KMT2A
SCHEMBL4423724 0.84 L3MBTL1 (0.39) POLBL3MBTL1DRD3KCNH2
SCHEMBL8773320 0.83 GNAI3 (0.42) POLBMEN1KMT2ADRD2SIGMAR1
SCHEMBL7044546 0.82 MEN1 (0.42) NPC1RAB9AMEN1KMT2AL3MBTL1
SCHEMBL10416569 0.81 FKBP1A (0.41) MEN1KMT2ADRD2L3MBTL1DRD3
SCHEMBL8089341 0.81 FKBP1A (0.41) POLBMEN1KMT2AL3MBTL1
SCHEMBL8112327 0.80 L3MBTL1 (0.37) POLBKMT2ADRD2L3MBTL1DRD3
SCHEMBL10849278 0.80 L3MBTL1 (0.37) POLBMEN1KMT2AL3MBTL1DRD3
SCHEMBL9814986 0.80 L3MBTL1 (0.41) POLBL3MBTL1DRD3KCNH2
SCHEMBL750534 0.79 L3MBTL1 (0.39) POLBMEN1KMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0670316-B1 1,3,6-Trialkylhexahydro-1,3,6-triazocine-2-one and preparation process thereof MITSUI TOATSU CHEMICALS (JP) 1997-09-03 EP disclosed
US-5514793-A 1,3,6-trialkylhexahydro-1,3,6-triazocine-2-on and preparation process thereof MITSUI TOATSU CHEMICALS, INC. (JP) 1996-05-07 US disclosed
EP-0670316-A1 1,3,6-Trialkylhexahydro-1,3,6-triazocine-2-one and preparation process thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1995-09-06 EP disclosed