SCHEMBL8773450

SCHEMBL8773450

CCc1ccccc1C(=O)NO

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
KDM4E B2RXH2 1/20 0.55
MPO P05164 1/20 0.55
HIF1A Q16665 1/20 0.55
HDAC8 Q9BY41 3/20 0.50
MMP3 P08254 1/20 0.50
F2R P25116 1/20 0.50
HTT P42858 2/20 0.49
LMNA P02545 2/20 0.48
CLCN2 P51788 1/20 0.46
HDAC3 O15379 2/20 0.45
HDAC1 Q13547 2/20 0.45
HDAC7 Q8WUI4 2/20 0.45
HDAC2 Q92769 2/20 0.45
HDAC6 Q9UBN7 2/20 0.45
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
IDO1 P14902 1/20 0.45
ALOX15 P16050 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11148178 0.83 HTT (0.50) GAASMN1; SMN2KDM4EMPOHIF1A
SCHEMBL5954191 0.83 GAA (0.57) GAAKDM4EF2RHTTLMNA
SCHEMBL1098843 0.83 GAA (0.62) GAASMN1; SMN2KDM4EMPOHIF1A
SCHEMBL3135538 0.83 CTSD (0.56) GAAKDM4EF2RHTTLMNA
SCHEMBL7097581 0.82 L3MBTL1 (0.57) GAAKDM4EF2RHTTLMNA
Formic Acid SCHEMBL31492527 0.81 KDR (0.45) GAASMN1; SMN2KDM4EMPOHIF1A
SCHEMBL27690336 0.81 LIPG (0.51) HTTTSHR
SCHEMBL14731239 0.80 HPGD (0.50) GAAKDM4EF2RHTTLMNA
SCHEMBL16478564 0.80 HPGD (0.54) GAAKDM4EF2RHTTLMNA
SCHEMBL20341235 0.80 F2R (0.48) GAAF2RHTTLMNACLCN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119431189-A Hydroxamic acid compound and application thereof 惠州市第一人民医院 2025-02-14 CN disclosed
US-20220168717-A1 NOVEL METAL COMPLEX, METHOD FOR PRODUCING SAME, AND METHOD FOR PRODUCING GAMMA-LACTAM COMPOUND USING SAME INSTITUTE FOR BASIC SCIENCE (KR) 2022-06-02 US disclosed
US-11344872-B2 Metal complex, method for producing same, and method for producing gamma-lactam compound using same INSTITUTE FOR BASIC SCIENCE (KR) 2022-05-31 US disclosed
US-20200330969-A1 NOVEL METAL COMPLEX, METHOD FOR PRODUCING SAME, AND METHOD FOR PRODUCING GAMMA-LACTAM COMPOUND USING SAME KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2020-10-22 US disclosed
US-10478829-B2 Collector compositions and methods of using same in mineral flotation processes CYTEC INDUSTRIES INC. (US) 2019-11-19 US disclosed
WO-2017091552-A1 COLLECTOR COMPOSITIONS AND METHODS OF USING SAME IN MINERAL FLOTATION PROCESSES CYTEC INDUSTRIES INC. (US) 2017-06-01 WO disclosed
US-20170144168-A1 COLLECTOR COMPOSITIONS AND METHODS OF USING SAME IN MINERAL FLOTATION PROCESSES CYTEC INDUSTRIES INC. (US) 2017-05-25 US disclosed
CN-106232584-A As the new compound of histone deacetylase 6 inhibitor and the pharmaceutical composition comprising it 株式会社钟根堂 2016-12-14 CN disclosed
EP-3080125-A1 NOVEL AZAINDOLE DERIVATIVES AS SELECTIVE HISTONE DEACETYLASE (HDAC) INHIBITORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME Chong Kun Dang Pharmaceutical Corp. (KR) 2016-10-19 EP disclosed
WO-2015087151-A1 NOVEL AZAINDOLE DERIVATIVES AS SELECTIVE HISTONE DEACETYLASE (HDAC) INHIBITORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME CHONG KUN DANG PHARMACEUTICAL CORP. (KR) 2015-06-18 WO disclosed
CN-101296910-A Benzodiazepine and benzopiperazine analog inhibitors of histone deacetylase METHYLGENE INC (CA) 2008-10-29 CN disclosed
EP-0647217-B1 4-ACYLAMINOBENZAMIDES AND THEIR USE AS FUNGICIDES ZENECA LTD (GB) 1997-10-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220168717-A1 NOVEL METAL COMPLEX, METHOD FOR PRODUCING SAME, AND METHOD FOR PRODUCING GAMMA-LACTAM COMPOUND USING SAME COASY, NOTUM, MRPL21 GAA 132/4885SMN1; SMN2 3513/4885KDM4E 2491/4885
US-11344872-B2 Metal complex, method for producing same, and method for producing gamma-lactam compound using same COASY, NOTUM, MRPL21 GAA 105/4885SMN1; SMN2 3219/4885KDM4E 2141/4885
US-20200330969-A1 NOVEL METAL COMPLEX, METHOD FOR PRODUCING SAME, AND METHOD FOR PRODUCING GAMMA-LACTAM COMPOUND USING SAME COASY, NOTUM, MRPL21 GAA 132/4885SMN1; SMN2 3513/4885KDM4E 2491/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.