SCHEMBL8773896 — predicted protein targets

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	MME	P08473	2/20	0.60

▸	MMP3	P08254	13/20	0.57

▸	MMP2	P08253	12/20	0.57

▸	MMP1	P03956	8/20	0.57

▸	MMP9	P14780	5/20	0.57

▸	MMP8	P22894	1/20	0.57

▸	MMP13	P45452	1/20	0.57

▸	MMP14	P50281	1/20	0.57

▸	ADAM17	P78536	1/20	0.57

▸	MMP7	P09237	1/20	0.49

▸	PDF	Q9HBH1	1/20	0.49

▸	RRM1	P23921	1/20	0.44

▸	RRM2	P31350	1/20	0.44

▸	RRM2B	Q7LG56	1/20	0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL5088865	0.88	MMP3 (0.74)	MMEMMP3MMP2MMP1MMP9
SCHEMBL4633112	0.88	MMP3 (0.74)	MMEMMP3MMP2MMP1MMP9
SCHEMBL8777512	0.86	MMP3 (0.59)	MMEMMP3MMP2MMP1MMP9
SCHEMBL21994104	0.79	MME (0.67)	MMEMMP3MMP2MMP1MMP9
SCHEMBL7368385	0.78	MME (0.81)	MMEMMP3MMP2MMP1MMP9
SCHEMBL8777504	0.78	MMP2 (0.57)	MMP3MMP2MMP1MMP9MMP8
SCHEMBL27501940	0.77	SLC7A5 (0.52)	MMP3MMP2MMP1MMP9MMP8
SCHEMBL7049300	0.77	SLC7A5 (0.52)	MMP3MMP2MMP1MMP9MMP8
SCHEMBL7758593	0.77	MMP2 (0.69)	MMP3MMP2MMP1MMP9MMP8
SCHEMBL17969297	0.75	MMP1 (0.45)	MMEMMP3MMP2MMP1MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0793643-A1	MATRIX METALLOPROTEASE INHIBITORS	SYNTEX (U.S.A.) INC. (US)	1997-09-10	—	—	EP	disclosed
WO-1996016027-A1	MATRIX METALLOPROTEASE INHIBITORS	SYNTEX (U.S.A.) INC. (US)	1996-05-30	—	—	WO	disclosed