Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.41 |
| ▸ | MMP9 | P14780 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8773916 | 0.73 | NPY5R (0.44) | LMNAALDH1A1L3MBTL1TP53RAB9A | |
| SCHEMBL8987839 | 0.70 | MMP2 (0.41) | MMP2MMP9NPSR1LMNAGAA | |
| SCHEMBL8987840 | 0.68 | MMP2 (0.40) | MMP2MMP9NPSR1LMNAGAA | |
| SCHEMBL28763259 | 0.67 | MT-CO2 (0.57) | NPSR1LMNAGAAMT-CO2ALDH1A1 | |
| SCHEMBL8987900 | 0.63 | MAPK14 (0.38) | MMP2MMP9NPSR1LMNAGAA | |
| SCHEMBL14472417 | 0.62 | HAO1 (0.36) | NPSR1LMNAGAATP53MAPT | |
| SCHEMBL11142995 | 0.62 | ALDH1A1 (0.51) | NPSR1LMNAGAAALDH1A1MAPT | |
| SCHEMBL197621 | 0.61 | NPSR1 (0.56) | NPSR1LMNAGAAMT-CO2ALDH1A1 | |
| SCHEMBL24806572 | 0.60 | GAA (0.60) | NPSR1LMNAGAAALDH1A1TP53 | |
| SCHEMBL11271112 | 0.60 | ALDH1A1 (0.44) | MMP2MMP9LMNAALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0802907-A1 | ACYLATED 5-AMINOPYRAZOLES AND THE USE THEREOF TO COMBAT ANIMAL PARASITES | BAYER AG (DE) | 1997-10-29 | — | — | EP | disclosed |
| WO-1996021653-A1 | ACYLATED 5-AMINOPYRAZOLES AND THE USE THEREOF TO COMBAT ANIMAL PARASITES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-07-18 | — | — | WO | disclosed |