Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 2/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | KLK7 | P49862 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8329943 | 0.74 | NOD2 (0.48) | LTA4HEPHX2ALDH1A1L3MBTL1CSNK1D | |
| SCHEMBL7621606 | 0.73 | MAPK1 (0.45) | LTA4HEPHX2ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL8773935 | 0.73 | MMP2 (0.41) | ALDH1A1L3MBTL1RAB9AMEN1KMT2A | |
| SCHEMBL7623076 | 0.72 | MAPK1 (0.43) | LTA4HEPHX2MAPK1L3MBTL1CSNK1D | |
| SCHEMBL7618791 | 0.70 | MAPK1 (0.46) | LTA4HEPHX2ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL8987834 | 0.70 | KMT2A (0.51) | LTA4HEPHX2ALDH1A1GSK3AL3MBTL1 | |
| SCHEMBL8987836 | 0.69 | KMT2A (0.53) | LTA4HEPHX2ALDH1A1GSK3AL3MBTL1 | |
| SCHEMBL6446114 | 0.66 | KMT2A (0.56) | LTA4HEPHX2ALDH1A1RAB9ANPC1 | |
| SCHEMBL1143274 | 0.66 | RAB9A (0.46) | NPY5RRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL2367221 | 0.66 | POLB (0.56) | LTA4HEPHX2ALDH1A1L3MBTL1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0802907-A1 | ACYLATED 5-AMINOPYRAZOLES AND THE USE THEREOF TO COMBAT ANIMAL PARASITES | BAYER AG (DE) | 1997-10-29 | — | — | EP | disclosed |
| WO-1996021653-A1 | ACYLATED 5-AMINOPYRAZOLES AND THE USE THEREOF TO COMBAT ANIMAL PARASITES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-07-18 | — | — | WO | disclosed |