Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.51 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.51 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.51 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.51 |
| ▸ | THPO | P40225 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28632640 | 0.87 | LMNA (0.54) | MAPTPTGS1CXCR1CXCR2PTGS2 | |
| Benzene SCHEMBL11583205 | 0.87 | FADS1 (0.60) | MAPTKDM4ELMNAALDH1A1HPGD | |
| SCHEMBL4854892 | 0.85 | ALDH1A1 (0.55) | MAPTPTGS1CXCR1CXCR2PTGS2 | |
| SCHEMBL12569599 | 0.85 | FADS1 (0.61) | MAPTKDM4ELMNAMEN1KMT2A | |
| SCHEMBL29639822 | 0.85 | FADS1 (0.61) | MAPTKDM4ELMNAMEN1KMT2A | |
| SCHEMBL24166526 | 0.83 | MEN1 (0.73) | MAPTKDM4ELMNAMEN1KMT2A | |
| SCHEMBL11574129 | 0.82 | GAA (0.51) | MAPTKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL26999640 | 0.82 | MEN1 (0.53) | MAPTKDM4ELMNAALDH1A1HPGD | |
| SCHEMBL3430494 | 0.81 | MEN1 (0.51) | MAPTKDM4ELMNAALDH1A1MEN1 | |
| SCHEMBL729868 | 0.81 | PTGS1 (0.56) | MAPTPTGS1CXCR1CXCR2PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0804425-A2 | BENZODIAZEPINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-11-05 | — | — | EP | disclosed |