Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | GCGR | P47871 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8775030 | 0.99 | GAA (0.35) | GAAMAPTGCGR | |
| SCHEMBL8774099 | 0.97 | GAA (0.31) | GAAMAPTGCGR | |
| SCHEMBL8774414 | 0.92 | TRPV3 (0.32) | — | |
| SCHEMBL8774393 | 0.90 | GAA (0.32) | GAAMAPTGCGR | |
| SCHEMBL8774613 | 0.87 | TRPV3 (0.37) | — | |
| SCHEMBL9244209 | 0.85 | GAA (0.34) | GAAMAPT | |
| SCHEMBL9250236 | 0.84 | GAA (0.36) | GAAMAPTGCGR | |
| SCHEMBL9154681 | 0.83 | GAA (0.33) | GAAMAPT | |
| SCHEMBL8774053 | 0.83 | RARB (0.38) | GAAMAPT | |
| SCHEMBL8774058 | 0.83 | RARB (0.38) | GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0519370-B1 | Heterocyclic derivatives | MERCK PATENT GMBH (DE) | 1997-11-05 | — | — | EP | disclosed |
| EP-0519370-A2 | Heterocyclic derivatives | MERCK PATENT GmbH (DE) | 1992-12-23 | — | — | EP | disclosed |