Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | APLNR | P35414 | 4/20 | 0.33 |
| ▸ | GCGR | P47871 | 3/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9244209 | 0.99 | GAA (0.34) | GAAMAPTAPLNR | |
| SCHEMBL9250333 | 0.95 | APLNR (0.34) | GAAMAPTAPLNR | |
| SCHEMBL9766719 | 0.93 | APLNR (0.33) | GAAAPLNR | |
| SCHEMBL9249912 | 0.91 | APLNR (0.32) | APLNR | |
| SCHEMBL9154681 | 0.88 | GAA (0.33) | GAAMAPT | |
| SCHEMBL9253040 | 0.86 | TRPV3 (0.33) | APLNR | |
| SCHEMBL8775030 | 0.86 | GAA (0.35) | GAAMAPTGCGR | |
| SCHEMBL8774050 | 0.84 | GAA (0.34) | GAAMAPTGCGR | |
| SCHEMBL9159148 | 0.84 | MEN1 (0.31) | GAA | |
| SCHEMBL9766630 | 0.83 | MEN1 (0.30) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445248-B1 | PYRIDINE DERIVATIVES | MERCK PATENT GMBH (DE) | 1995-03-08 | — | — | EP | disclosed |
| EP-0445248-A1 | PYRIDINE DERIVATIVES. | MERCK PATENT GMBH (DE) | 1991-09-11 | — | — | EP | disclosed |
| WO-1991004248-A1 | PYRIDINE DERIVATIVES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1991-04-04 | — | — | WO | disclosed |