Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | GCGR | P47871 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8774050 | 0.97 | GAA (0.34) | GAAMAPTGCGR | |
| SCHEMBL8775030 | 0.96 | GAA (0.35) | GAAMAPTGCGR | |
| SCHEMBL8774414 | 0.93 | TRPV3 (0.32) | — | |
| SCHEMBL8774613 | 0.88 | TRPV3 (0.37) | — | |
| SCHEMBL8774393 | 0.87 | GAA (0.32) | GAAMAPTGCGR | |
| SCHEMBL9250333 | 0.85 | APLNR (0.34) | GAAMEN1MAPK1KMT2AMAPT | |
| SCHEMBL9159148 | 0.83 | MEN1 (0.31) | GAAMEN1MAPK1KMT2A | |
| SCHEMBL9766719 | 0.83 | APLNR (0.33) | GAAMEN1MAPK1KMT2A | |
| SCHEMBL8775149 | 0.83 | SLC6A2 (0.32) | — | |
| SCHEMBL8774107 | 0.82 | GPR84 (0.38) | GAAMEN1MAPK1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0519370-B1 | Heterocyclic derivatives | MERCK PATENT GMBH (DE) | 1997-11-05 | — | — | EP | disclosed |
| EP-0519370-A2 | Heterocyclic derivatives | MERCK PATENT GmbH (DE) | 1992-12-23 | — | — | EP | disclosed |