SCHEMBL877580

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15712003	0.66	KDM4E (0.35)	GAARECQLKDM4ETHRBL3MBTL1
	SCHEMBL12285505	0.65	—	—
	SCHEMBL17525125	0.65	GAA (0.50)	GAARECQLKDM4ETHRBL3MBTL1
	SCHEMBL1009003	0.65	L3MBTL1 (0.67)	GAARECQLKDM4ETHRBL3MBTL1
	SCHEMBL21395297	0.63	RAB9A (0.40)	GAARECQLKDM4ETHRBL3MBTL1
	SCHEMBL21991169	0.63	KDM4E (0.62)	GAARECQLKDM4ETHRBL3MBTL1
	SCHEMBL7252699	0.62	L3MBTL1 (1.00)	GAARECQLKDM4ETHRBL3MBTL1
	SCHEMBL15690207	0.61	—	—
	SCHEMBL17291049	0.61	—	—
	SCHEMBL964578	0.61	KDM4E (0.45)	GAARECQLKDM4ETHRBL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.