Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.63 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
| ▸ | CFTR | P13569 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21396941 | 0.85 | TDP1 (0.57) | EPHX2CYP2C19SMN1; SMN2HSD11B1LMNA | |
| SCHEMBL8775812 | 0.83 | TBXAS1 (0.65) | TBXAS1EPHX2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL17596760 | 0.80 | TBXAS1 (0.60) | TBXAS1EPHX2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL9199313 | 0.79 | PLOD2 (0.79) | TBXAS1CYP2C9CYP2C19PLOD2SMN1; SMN2 | |
| SCHEMBL28296835 | 0.78 | TBXAS1 (0.58) | TBXAS1EPHX2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL8699682 | 0.77 | TBXAS1 (0.60) | TBXAS1EPHX2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL8775807 | 0.77 | TBXAS1 (0.82) | TBXAS1EPHX2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL8775856 | 0.77 | TBXAS1 (0.82) | TBXAS1EPHX2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL11990053 | 0.76 | TBXAS1 (0.63) | TBXAS1EPHX2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL8775789 | 0.74 | SMN1; SMN2 (0.58) | TBXAS1EPHX2CYP2C9CYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807626-A1 | N-HYDROXYUREA DERIVATIVES | Nikken Chemicals Company, Limited (JP) | 1997-11-19 | — | — | EP | disclosed |