Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CFTR | P13569 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7178642 | 0.87 | ALDH1A1 (0.55) | LMNASMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL5929541 | 0.85 | LMNA (0.48) | LMNATBXAS1SMN1; SMN2PDE4DKCNA5 | |
| SCHEMBL2370448 | 0.85 | L3MBTL1 (0.47) | LMNATBXAS1SMN1; SMN2KCNA5MEN1 | |
| SCHEMBL5160706 | 0.85 | LMNA (0.48) | LMNATBXAS1SMN1; SMN2PDE4DKCNA5 | |
| SCHEMBL27396676 | 0.85 | ITGB3 (0.45) | TBXAS1KCNA5MEN1KMT2A | |
| SCHEMBL1294805 | 0.84 | LMNA (0.43) | LMNATBXAS1SMN1; SMN2PDE4DKCNA5 | |
| SCHEMBL1294809 | 0.84 | LMNA (0.43) | LMNATBXAS1SMN1; SMN2PDE4DKCNA5 | |
| SCHEMBL16462158 | 0.84 | ALDH1A1 (0.45) | LMNAMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL7130315 | 0.84 | LMNA (0.43) | LMNATBXAS1SMN1; SMN2PDE4DKCNA5 | |
| SCHEMBL27224522 | 0.84 | MEN1 (0.44) | LMNATBXAS1SMN1; SMN2PDE4DKCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807626-A1 | N-HYDROXYUREA DERIVATIVES | Nikken Chemicals Company, Limited (JP) | 1997-11-19 | — | — | EP | disclosed |