SCHEMBL8775893

SCHEMBL8775893

O=S(=O)(O)c1cc(O)ccc1-c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.57
ESR2 Q92731 5/20 0.52
ESR1 P03372 4/20 0.47
POLB P06746 2/20 0.47
GAA P10253 1/20 0.47
GFER P55789 1/20 0.47
HPGD P15428 2/20 0.44
HSD17B10 Q99714 2/20 0.44
LMNA P02545 1/20 0.44
HIF1A Q16665 1/20 0.44
CYP26A1 O43174 2/20 0.43
BACE1 P56817 1/20 0.43
PELI1 Q96FA3 1/20 0.42
KDM4E B2RXH2 2/20 0.42
ALDH1A1 P00352 2/20 0.42
MEN1 O00255 1/20 0.42
MAPT P10636 1/20 0.42
MPI P34949 1/20 0.42
KMT2A Q03164 1/20 0.42
MAOA P21397 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4889861 0.89 HSD17B10 (0.48) ALOX5ESR2ESR1HPGDHSD17B10
SCHEMBL9721409 0.87 ALOX5 (0.59) ALOX5ESR2ESR1POLBGAA
SCHEMBL8365855 0.85 ALOX5 (0.52) ALOX5ESR2ESR1POLBGAA
SCHEMBL360271 0.84 LMNA (0.52) ESR2ESR1POLBGAAGFER
SCHEMBL27765267 0.84 ALOX5 (0.55) ALOX5ESR2ESR1POLBGAA
SCHEMBL1658554 0.84 ALOX5 (0.60) ALOX5ESR2ESR1POLBGAA
SCHEMBL87476 0.83 LMNA (0.45) ALOX5ESR2ESR1POLBGAA
SCHEMBL1456426 0.80 PTPRC (0.43) ALOX5HSD17B10BACE1ALDH1A1MEN1
SCHEMBL6952564 0.80 MAPT (0.40) BACE1MEN1MAPTKMT2ASMN1; SMN2
SCHEMBL27605511 0.80 HDAC7 (0.45) ESR2HPGDLMNAKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0643736-B1 Thermally stable electrically conductive conjugated polymer complexes having hydrogen bonding counterions ALLIED SIGNAL INC (US) 1997-11-26 EP disclosed
US-5422423-A Polyanilines doped with anions such as sulfonates, phosphonate , borates, phosphinates amd sulfinates ALLIEDSIGNAL INC. (US) 1995-06-06 US disclosed
US-3985797-A Hydroxylation of aromatic compounds UOP INC. (US) 1976-10-12 US disclosed
US-3985796-A Hydroxylation of aromatic compounds UOP INC. (US) 1976-10-12 US disclosed
US-3931295-A Hydroxylation of aromatic compounds UNIVERSAL OIL PRODUCTS COMPANY (US) 1976-01-06 US disclosed