SCHEMBL87476

SCHEMBL87476

O=S(=O)(O)c1ccccc1-c1ccc(O)cc1S(=O)(=O)O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.45
HPGD P15428 1/20 0.45
HIF1A Q16665 1/20 0.45
HSD17B10 Q99714 1/20 0.45
PGAM1 P18669 1/20 0.45
POLB P06746 1/20 0.44
GAA P10253 1/20 0.44
GFER P55789 1/20 0.44
ALPL P05186 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
ALPI P09923 1/20 0.43
ALPG P10696 1/20 0.43
DNMT1 P26358 1/20 0.43
MCL1 Q07820 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
ESR1 P03372 3/20 0.42
ESR2 Q92731 3/20 0.42
MAOA P21397 2/20 0.42
MAOB P27338 2/20 0.42
UGT1A1 P22309 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL360271 0.90 LMNA (0.52) LMNAHPGDHIF1AHSD17B10PGAM1
SCHEMBL11179337 0.84 LMNA (0.51) LMNAHPGDHIF1AHSD17B10POLB
SCHEMBL458284 0.83 SMN1; SMN2 (0.48) LMNAPGAM1POLBGAAALPL
SCHEMBL8775893 0.83 ALOX5 (0.57) LMNAHPGDHIF1AHSD17B10POLB
SCHEMBL28837581 0.81 SMN1; SMN2 (0.46) LMNAPGAM1POLBGAAALPL
SCHEMBL19391945 0.79 ALDH1A1 (0.53) LMNAHPGDHSD17B10PGAM1POLB
SCHEMBL7788575 0.79 SMN1; SMN2 (0.50) LMNAPGAM1POLBGAAL3MBTL1
SCHEMBL4889861 0.78 HSD17B10 (0.48) LMNAHPGDHIF1AHSD17B10ESR1
SCHEMBL890902 0.78 ABL1 (0.48) LMNAPGAM1GAAESR1ESR2
SCHEMBL16583502 0.78 SMN1; SMN2 (0.50) LMNAHSD17B10PGAM1L3MBTL1MCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1073 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020068665-A1 USE OF COLLAGEN BINDING DOMAINS TO DELIVER PRODUCTS TO SKIN FABIUS BIOTECHNOLOGY (US) 2020-04-02 WO claimed
US-20140127275-A1 Composition Containing a Cellulose Derived Capsule With A Sunscreen CoLabs International Corporation (US) 2014-05-08 US claimed
EP-2367852-A1 COSMETIC COMPOSITION CONTAINING ACETYLATED OLIGOGLUCURONANS Sederma (FR) 2011-09-28 EP claimed
US-20110008272-A1 Use of Creatine or Creatine Compounds for Skin Preservation AVICENA GROUP, INC. (US) 2011-01-13 US claimed
WO-2010067327-A1 COSMETIC COMPOSITION CONTAINING ACETYLATED OLIGOGLUCURONANS SEDERMA (FR) 2010-06-17 WO claimed
WO-2010044076-A2 COSMETIC AND TOPICAL USE OF XANTHOHUMOL INCLUDING BRIGHTENING SKIN COMPLEXION AND REDUCING CUTANEOUS REDNESS SEDERMA (FR) 2010-04-22 WO claimed
US-20060193789-A1 Surfacant, film forming agent, water, gas propellant; plant and animal extracts and oils; may include malathion FOAMIX LTD. (IL) 2006-08-31 US claimed
EP-1495103-A4 TARGETED CONTROLLED DELIVERY COMPOSITIONS ACTIVATED BY CHANGES IN PH OR SALT CONCENTRATION SALVONA LLC (US) 2006-03-22 EP claimed
US-20050186158-A1 Use of creatine or creatine compounds for skin preservation AVICENA GROUP, INC. (US) 2005-08-25 US claimed
US-6897281-B2 Breathable polyurethanes, blends, and articles NOVEON IP HOLDINGS CORP. (US) 2005-05-24 US claimed
EP-1495103-A1 TARGETED CONTROLLED DELIVERY COMPOSITIONS ACTIVATED BY CHANGES IN PH OR SALT CONCENTRATION Salvona L.L.C. (US) 2005-01-12 EP claimed
WO-2003087287-A1 TARGETED CONTROLLED DELIVERY COMPOSITIONS ACTIVATED BY CHANGES IN PH OR SALT CONCENTRATION SALVONA L.L.C. (US) 2003-10-23 WO claimed
US-20030195133-A1 Targeted controlled delivery compositions activated by changes in pH or salt concentration SALVONA L.L.C. 2003-10-16 US claimed
US-5837697-A CONTAINING SALICYLIC ACID, SUNSCREEN AGENT AND A CARRIER THE PROCTER & GAMBLE COMPANY (US) 1998-11-17 US claimed
US-11957769-B2 Polyhydroxy fullerene sunscreen active agents and compositions THE CLEVELAND CLINIC FOUNDATION (US) 2024-04-16 US disclosed
US-20240099948-A1 Compositions Comprising Silicon Dioxide-Based Particles Including One or More Agents COLABS INT'L CORP. (US) 2024-03-28 US disclosed
EP-4329521-A2 COLLAGEN COMPOSITIONS AND METHODS OF USE THEREOF Modern Meadow, Inc. (US) 2024-03-06 EP disclosed
US-4847069-A SUNSCREEN AGENTS THE PROCTER & GAMBLE COMPANY (US) 1989-07-11 US disclosed
EP-0313305-A2 Photoprotection compositions comprising chelating agents THE PROCTER & GAMBLE COMPANY (US) 1989-04-26 EP disclosed
US-4098881-A COMPOSITIONS TO CONTROL THE CHRONIC EFFECTS OF EXPOSURE TO SUNLIGHT COMPRISING CONJUGATED DIENES THE PROCTER & GAMBLE COMPANY (US) 1978-07-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110008272-A1 Use of Creatine or Creatine Compounds for Skin Preservation PC, CKMT1A; CKMT1B, CHEK1 LMNA 1116/4885HPGD 606/4885HIF1A 1913/4885
US-20030195133-A1 Targeted controlled delivery compositions activated by changes in pH or salt concentration TRPC5, TRPV1, TRPV2 LMNA 4180/4885HPGD 1445/4885HIF1A 423/4885
US-20140127275-A1 Composition Containing a Cellulose Derived Capsule With A Sunscreen MSH6, TYR, CUTA LMNA 3451/4885HPGD 1979/4885HIF1A 4292/4885
US-20050186158-A1 Use of creatine or creatine compounds for skin preservation PC, CKMT1A; CKMT1B, CHEK1 LMNA 1116/4885HPGD 606/4885HIF1A 1913/4885
US-20240099948-A1 Compositions Comprising Silicon Dioxide-Based Particles Including One or More Agents MSN, LIPE, CUTA LMNA 3449/4885HPGD 4237/4885HIF1A 4443/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.